An application of field-effect sensors for in-situ monitoring of degradation of biopolymers
- The characterization of the degradation kinetics of biodegradable polymers is mandatory with regard to their proper application. In the present work, polymer-modified electrolyte–insulator–semiconductor (PMEIS) field-effect sensors have been applied for in-situ monitoring of the pH-dependent degradation kinetics of the commercially available biopolymer poly(d,l-lactic acid) (PDLLA) in buffer solutions from pH 3 to pH 13. PDLLA films of 500 nm thickness were deposited on the surface of an Al–p-Si–SiO2–Ta2O5 structure from a polymer solution by means of spin-coating method. The PMEIS sensor is, in principle, capable to detect any changes in bulk, surface and interface properties of the polymer induced by degradation processes. A faster degradation has been observed for PDLLA films exposed to alkaline solutions (pH 9, pH 11 and pH 13).
| Verfasserangaben: | Sebastian Schusser, Arshak PoghossianORCiD, Matthias Bäcker, M. Krischer, Marcel Leinhos, P. Wagner, Michael Josef SchöningORCiD |
|---|---|
| DOI: | https://doi.org/10.1016/j.snb.2014.10.058 |
| ISSN: | 1873-3077 (E-Journal); 0925-4005 (Print) |
| Titel des übergeordneten Werkes (Englisch): | Sensors and actuators B: Chemical |
| Verlag: | Elsevier |
| Verlagsort: | Amsterdam |
| Dokumentart: | Wissenschaftlicher Artikel |
| Sprache: | Englisch |
| Erscheinungsjahr: | 2015 |
| Datum der Publikation (Server): | 28.10.2014 |
| Jahrgang: | 207, Part B |
| Erste Seite: | 954 |
| Letzte Seite: | 959 |
| Link: | https://doi.org/10.1016/j.snb.2014.10.058 |
| Zugriffsart: | campus |
| Fachbereiche und Einrichtungen: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
| FH Aachen / INB - Institut für Nano- und Biotechnologien | |
| collections: | Verlag / Elsevier |
