Refine
Year of publication
- 2015 (22) (remove)
Document Type
- Article (17)
- Part of a Book (3)
- Conference Proceeding (1)
- Patent (1)
Language
- English (22) (remove)
Has Fulltext
- no (22) (remove)
Institute
- Fachbereich Chemie und Biotechnologie (22) (remove)
The invention relates to a method for production of single-stranded macronucleotides by amplifying and ligating an extended monomeric single-stranded target nucleic acid sequence (targetss) into a repetitive cluster of double-stranded target nucleic acid sequences (targetds), and subsequently cloning the construct into a vector (aptagene vector). The aptagene vector is transformed into host cells for replication of the aptagene and isolated in order to optain single-stranded target sequences (targetss). The invention also relates to single-stranded nucleic acids, produced by a method of the invention.