Article
Refine
Year of publication
Document Type
- Article (1531) (remove)
Has Fulltext
- no (1531) (remove)
Keywords
- LAPS (4)
- CellDrum (3)
- hydrogen peroxide (3)
- Bacillus atrophaeus (2)
- Empirical process (2)
- Field-effect sensor (2)
- Goodness-of-fit test (2)
- Independence test (2)
- Light-addressable potentiometric sensor (2)
- Paired sample (2)
- Parametric bootstrap (2)
- Raman spectroscopy (2)
- Stiffness (2)
- constructive alignment (2)
- damage (2)
- examination (2)
- field-effect sensor (2)
- frequency mixing magnetic detection (2)
- impedance spectroscopy (2)
- likelihood ratio test (2)
- locomotion (2)
- long-term retention (2)
- multimodal (2)
- muscle fascicle behavior (2)
- not identically distributed (2)
- practical learning (2)
- tobacco mosaic virus (TMV) (2)
- ultrasound (2)
- ultrasound imaging (2)
- (Bio)degradation (1)
- Acceleration (1)
- Achilles tendon (1)
- Adaptive control (1)
- Afterload (1)
- Ageing (1)
- AlterG (1)
- Alzheimer's disease (1)
- Anastomotic leakage (1)
- Anatomy (1)
- Annulus Fibrosus (1)
- Architectural gear ratio (1)
- Assistive technology (1)
- Asymptotic efficiency (1)
- Autolysis (1)
- Automatic control (1)
- Bacillus atrophaeus spores (1)
- Bacillus sp (1)
- Balance (1)
- Biocomposites (1)
- Biomechanical simulation (1)
- Biosolubilization (1)
- Booster Station (1)
- Bootstrap (1)
- Bootstrapping (1)
- Brownian Pillow (1)
- CNOT (1)
- Calorimetric gas sensor (1)
- Capacitive field-effect (1)
- Capacitive model (1)
- Cardiac myocytes (1)
- Cardiac tissue (1)
- Categorial variable (1)
- Cell permeability (1)
- Cellular force (1)
- Cementoblast (1)
- Censored data (1)
- Chemical images (1)
- Chemical imaging sensor (1)
- Chemical sensor (1)
- Circular Dichroism (1)
- Co-managed care (1)
- Collective risk model (1)
- Competitiveness (1)
- Complex System (1)
- Complex-valued eigenvalues (1)
- Compliance (1)
- Compression (1)
- Computational biomechanics (1)
- Concomitant (1)
- Conductive Boundary Condition (1)
- Constitutive model (1)
- Contractile tension (1)
- Contractility (1)
- Coverage probability (1)
- Cramér-von-Mises statistic (1)
- Cramér-von-Mises test (1)
- Cross border adjustment mechanism (1)
- Crámer–von-Mises distance (1)
- C–V method (1)
- DNA biosensor (1)
- DNA hybridization (1)
- DPA (dipicolinic acid) (1)
- Damage mechanics theory (1)
- Decomposition (1)
- Deep Learning (1)
- Dehydrogenase (1)
- Diaphorase (1)
- Disc Degeneration (1)
- Discontinuous fractures (1)
- Discrete Optimization (1)
- Distorsion des oberen Sprunggelenks (1)
- Drug simulation (1)
- E-Mobility (1)
- EIS capacitive sensor (1)
- ES-FEM (1)
- Eigenvalue trajectories (1)
- Elderly (1)
- Electrolyte–insulator–semiconductor (1)
- Electromagnetism (1)
- Electromechanical modeling (1)
- Elektroenzephalographie (1)
- Elemental (1)
- End-to-end colorectal anastomosis (1)
- Endothelial cells (1)
- Endothelial dysfunction (1)
- Energy-intensive industry (1)
- Enzymatic biosensor (1)
- Enzyme coverage (1)
- Enzyme logic gate (1)
- Equivalence test (1)
- Esophageal Doppler monitor (1)
- External knee adduction moments (1)
- FS-FEM (1)
- Fall prevention (1)
- Field effect (1)
- Field-effect biosensor (1)
- Finite element analysis (1)
- Finite element modelling (1)
- Floor prices (1)
- Force (1)
- Forces (1)
- Fracture configuration (1)
- Fracture simulation (1)
- Freeze–thaw process (1)
- Frequency adaption (1)
- Frequency mixing magnetic detection (1)
- Functional Delta Method (1)
- Gamma distribution (1)
- Glaucoma (1)
- Goodness-of-fit tests for uniformity (1)
- Ground-level falls (1)
- Hadamard differentiability (1)
- Haemodialysis (1)
- Handbike (1)
- Heart tissue culture (1)
- Heterostructure (1)
- Hodgkin–Huxley models (1)
- Hoeffding-Blum-Kiefer-Rosenblatt independence test (1)
- Homogenization (1)
- Hotelling’s T² test (1)
- Human-Computer interaction (1)
- Hydrogen peroxide (1)
- Image Reconstruction (1)
- Impedance spectroscopy (1)
- Incomplete data (1)
- Induced pluripotent stem cells (1)
- Inotropic compounds (1)
- Integrated empirical distribution (survival) function (1)
- Interior transmission problem (1)
- Intervertebral Disc (1)
- Intradiscal Pressure (1)
- Inverse Scattering (1)
- Inverse dynamic problem (1)
- Inverse kinematic problem (1)
- Ion channels (1)
- Iterative learning control (1)
- Kinetic energy (1)
- LPS (1)
- Lab-on-Chip (1)
- Label-free detection (1)
- Langevin theory (1)
- Layer-by-layer adsorption (1)
- LbL films (1)
- Light-addressable Potentiometric Sensor (1)
- Lipopolysaccharide (1)
- Liver (1)
- Long COVID (1)
- MOS (1)
- Machine learning (1)
- Magnetic nanoparticles (1)
- Manipulated variables (1)
- Marginal homogeneity test (1)
- Mechanotransduction (1)
- Metascintillator (1)
- Microcirculation (1)
- Micromagnetic simulation (1)
- Mild cognitive impairment (1)
- Mobility (1)
- Mobility tests (1)
- Mobility transition (1)
- Multi-criteria decision analysis (1)
- Multi-sample problem (1)
- Multianalyte detection (1)
- Multiple TOF kernels (1)
- Muscle (1)
- Muscle Fascicle (1)
- Muscle Force (1)
- Musculoskeletal model (1)
- Musculoskeletal system (1)
- Myocardial infarction and cardiac death (1)
- NONOate (1)
- Natural fibres (1)
- Negative impedance convertor (1)
- Neural Network (1)
- Nitric Oxide (1)
- Nitric Oxide Donor (1)
- Non-parallel fissures (1)
- Nonequilibrium dynamics (1)
- Nonlinear Dynamics (1)
- Nucleus Pulposus (1)
- Numerical inversion of Laplace transforms (1)
- Numerical linear algebra (1)
- O2 plasma (1)
- Ocular blood flow (1)
- Organic light-emitting diode display (1)
- Paralympic sport (1)
- Penicillin (1)
- Pharmacology (1)
- Physiology (1)
- Poly(allylamine hydrochloride) (1)
- Poly(d,l-lacticacid) (1)
- Polyimide (1)
- Polymer-matrix composites (1)
- Post-COVID-19 syndrome (1)
- Preference assessment (1)
- Product-integration (1)
- Proximal humerus fracture (1)
- Psychiatrische Biomarker (1)
- Pulsations (1)
- Pump System (1)
- RVA (1)
- Real-time monitoring (1)
- Recombinant activated protein C (1)
- Regionalization (1)
- Rehabilitation Technology and Prosthetics (1)
- Rehabilitation engineering (1)
- Resampling test (1)
- Resolvent Operator (1)
- Resonance-mode measurement (1)
- Retinal vessel analysis (1)
- Retinal vessels (1)
- Robotic rehabilitation (1)
- Rotator cuff (1)
- Running (1)
- S-FEM (1)
- ScaLAPACK (1)
- Schlafspindeldetektion (1)
- Semi-parametric random censorship model (1)
- Septic cardiomyopathy (1)
- Simulation (1)
- Simultaneous determination (1)
- Sn₃O₄ (1)
- Spleen (1)
- Sprunggelenkorthesen (1)
- Steel industry (1)
- Sterilisation process (1)
- Stress concentrations (1)
- SunRav BookEditor (1)
- Surgical Navigation and Robotics (1)
- Surgical staplers (1)
- Survival analysis (1)
- TMV adsorption (1)
- TOF PET (1)
- Ta₂O₅ gate (1)
- Technical Operations Research (TOR) (1)
- Tendon Rupture (1)
- Tendon properties (1)
- Tension (1)
- Tinetti test (1)
- Transmission Eigenvalues (1)
- Uniaxial compression test (1)
- Vapnik–Čhervonenkis class (1)
- Variable height stapler design (1)
- Vascular response (1)
- Vasomotions (1)
- Velocity (1)
- Visual field asymmetry (1)
- Volterra integral equation (1)
- Volume of confidence regions (1)
- Volume status (1)
- XOR (1)
- achilles tendon (1)
- actin cytoskeleton (1)
- adipose-derived stromal cells (ASCs) (1)
- adsorption (1)
- agility (1)
- allocation (1)
- anaesthetic complications (1)
- anisotropy (1)
- ankle braces (1)
- ankle sprain (1)
- annealing (1)
- aortic perfusion (1)
- artificial olfactory image (1)
- asymptotic relative efficiency (1)
- barium strontium titanate (1)
- biaxial tensile experiment (1)
- biomechanics (1)
- biopotential electrodes (1)
- biosensor (1)
- biosensors (1)
- bootstrap (1)
- calorimetric gas sensor (1)
- calorimetric gas sensor;hydrogen peroxide;wireless sensor system (1)
- capacitive field-effect sensor (1)
- carbonized rice husk (1)
- cardiomyocyte biomechanics (1)
- catalytic metal (1)
- cell aerosolization (1)
- cell atomization (1)
- central symmetry test (1)
- cerebral small vessel disease (1)
- chance constrained programming (1)
- chemical sensor (1)
- cognitive impairment (1)
- community dwelling (1)
- complete block symmetry (1)
- computational fluid dynamics analysis (1)
- conditional excess distribution (1)
- conditional expectation principle (1)
- confidence interval (1)
- connective tissue (1)
- constitutive modeling (1)
- contactless conductivity sensor (1)
- correlation (1)
- coupled Néel–Brownian relaxation dynamics (1)
- covariance principle (1)
- dental trauma (1)
- dialysis (1)
- difficult airway (1)
- distance learning (1)
- distorted element (1)
- double-lumen tube intubation (1)
- drop jump (1)
- e-books (1)
- e-issues (1)
- eigensolvers (1)
- electrolyte-insulator semiconductor sensor (EIS) (1)
- electromyography (1)
- electronic nose (1)
- endoluminal (1)
- endospores (1)
- energy absorption (1)
- energy dissipation (1)
- enzymatic (bio)degradation (1)
- enzyme cascade (1)
- exchangeability test (1)
- extracorporeal membrane oxygenation (1)
- fibulare Bandruptur (1)
- field-effect structure (1)
- force generation (1)
- forecast (1)
- forehead EEG (1)
- frequency mixing (1)
- functional data (1)
- gait (1)
- gas sensor (1)
- glucose oxidase (GOx) (1)
- goodness-of-fit test (1)
- healthy aging (1)
- heavy metals (1)
- hiPS cardiomyocytes (1)
- high-intensity exercise (1)
- high-k material (1)
- horseradish peroxidase (HRP) (1)
- huge dimensional data (1)
- humic acid (1)
- hydroxylation (1)
- hyper-gravity (1)
- hyperelastic (1)
- hypo-gravity (1)
- immobilization (1)
- in-ear EEG (1)
- in-situ monitoring (1)
- independence test (1)
- intraclass correlation coefficient (1)
- key performance indicators (1)
- lable-free detection (1)
- light-addressable potentiometric sensor (1)
- light-addressing technologies (1)
- lignite (1)
- limit analysis (1)
- lipopolysaccharide (1)
- magnetic actuation (1)
- magnetic beads (1)
- magnetic biosensing (1)
- magnetic nanoparticles (1)
- magnetic relaxation (1)
- magnetic sandwich immunoassay (1)
- magnetic sensing (1)
- magnetic separation (1)
- magnetic tweezers (1)
- magnetophoretic velocity (1)
- mechanical buffer (1)
- metal-oxide-semiconductor structure (1)
- micromagnetic simulation (1)
- multi-functional material (1)
- multinomial distribution (1)
- multiparametric immunoassays (1)
- multivariate normal distribution (1)
- muscle mechanics (1)
- nanobelts (1)
- non-simplex S-FEM elements (1)
- novel photoexcitation method (1)
- optical sensor setup (1)
- optical spore trapping (1)
- optical trapping (1)
- organosilanes (1)
- overload (1)
- parabolic flight (1)
- performance analysis (1)
- performance testing (1)
- physiology (1)
- plant virus detection (1)
- plug-based microfluidic device (1)
- poly(d, l-lactic acid) (1)
- portfolio risk (1)
- prevention (1)
- psychosocial (1)
- random effects (1)
- random effects meta-regression model (1)
- rehabilitation (1)
- reliability of structures (1)
- retinal microvasculature (1)
- retinal vessels (1)
- running (1)
- rupture of the fibular ligament (1)
- sEMG (1)
- sarcomere operating length (1)
- scanned light pulse technique (1)
- separable Hilbert space (1)
- series elastic element behavior (1)
- shakedown analysis (1)
- shoulder (1)
- silanization (1)
- simulation (1)
- smooth muscle contraction (1)
- softs (1)
- spatial resolution (1)
- sprint start (1)
- standard error of measurement (1)
- sterilisation (1)
- sterilization (1)
- sterilization conditions (1)
- stiffness (1)
- stochastic programming (1)
- strain energy function (1)
- stretch reflex (1)
- stretch-shortening cycle (1)
- superparamagnetic bead (1)
- superparamagnetic nanoparticles (1)
- surface functionalization (1)
- surface modification (1)
- survival (1)
- temperature (1)
- tendon rupture (1)
- test-retest reliability (1)
- tilted constant illumination (1)
- tri-lineage differentiation (1)
- turnip vein clearing virus (TVCV) (1)
- twin-fluid atomizer (1)
- ultrasonography (1)
- uniformly most powerful invariant test (1)
- unloading (1)
- videolaryngoscopy (1)
- virgin passive (1)
- viscoelasticity (1)
- visualization (1)
- walking (1)
- walking gait (1)
- · Psychiatrische Erkrankungen/Diagnostik (1)
Institute
- Fachbereich Medizintechnik und Technomathematik (1531) (remove)
Bonding of polymer-based microfluidics to polymer substrates still poses a challenge for Lab-On-a-Chip applications. Especially, when sensing elements are incorporated, patterned deposition of adhesives with curing at ambient conditions is required. Here, we demonstrate a fabrication method for fully printed microfluidic systems with sensing elements using inkjet and stereolithographic 3D-printing.
In this study, we show that synthetic sapphire (Al₂O₃), an established implant material, can also serve as a platform material for biosensors comparable to nanocrystalline diamond. Sapphire chips, beads, and powder were first modified with (3-aminopropyl) triethoxysilane (APTES), followed by succinic anhydride (SA), and finally single-stranded probe DNA was EDC coupled to the functionalized layer. The presence of the APTES-SA layer on sapphire powders was confirmed by thermogravimetric analyis and Fourier-transform infrared spectroscopy. Using planar sapphire chips as substrates and X-ray photoelectron spectroscopy (XPS) as surface-sensitive tool, the sequence of individual layers was analyzed with respect to their chemical state, enabling the quantification of areal densities of the involved molecular units. Fluorescence microscopy was used to demonstrate the hybridization of fluorescently tagged target DNA to the probe DNA, including denaturation- and re-hybridization experiments. Due to its high thermal conductivity, synthetic sapphire is especially suitable as a chip material for the heat-transfer method, which was employed to distinguish complementary- and non-complementary DNA duplexes containing single-nucleotide polymorphisms. These results indicate that it is possible to detect mutations electronically with a chemically resilient and electrically insulating chip material.
The sterilization of packages in aseptic food processes is highly significant to maintain a consumer-safe product with extended shelf-life. Today, the sterilization of food packages is predominantly accomplished by gaseous hydrogen peroxide (H2O2) in combination with heat. In order to monitor this sterilization process, calorimetric gas sensors as differential set-up of two platinum temperature sensors representing a catalytically active (additionally deposition of MnO2) and a passive segment have been recently developed. The temperature rise of the exothermic decomposition serves as an indicator of the present H2O2 concentration. In the present work, a theoretical approach considering the sensor’s thermochemistry and physical transport phenomena was formulated to evaluate the temperature rise based on the energy content of gaseous H2O2. In a further part of this work, three polymers have been analyzed with respect to their application as passivation materials. The examined polymers are photoresist SU-8, perfluoroalkoxy (PFA) and fluorinated ethylene propylene (FEP). Thermal analyses by means of differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) have been conducted to determine the operation limits of the polymers. The overall chemical resistance and stability of the polymers against the harsh environmental conditions during the sterilization process have been examined by attenuated total reflection Fourier transform infrared spectroscopy (ATR-FTIR).
The chemical imaging sensor was applied to in-situ pH imaging of the solution in the vicinity of a corroding surface of stainless steel under potentiostatic polarization. A test piece of polished stainless steel was placed on the sensing surface leaving a narrow gap filled with artificial seawater and the stainless steel was corroded under polarization. The pH images obtained during polarization showed correspondence between the region of lower pH and the site of corrosion. It was also found that the pH value in the gap became as low as 2 by polarization, which triggered corrosion.
Designing novel or optimizing existing biodegradable polymers for biomedical applications requires numerous tests on the effect of substances on the degradation process. In the present work, polymer-modified electrolyte–insulator–semiconductor (PMEIS) sensors have been applied for monitoring an enzymatically catalyzed degradation of polymers for the first time. The thin films of biodegradable polymer poly(d,l-lactic acid) and enzyme lipase were used as a model system. During degradation, the sensors were read-out by means of impedance spectroscopy. In order to interpret the data obtained from impedance measurements, an electrical equivalent circuit model was developed. In addition, morphological investigations of the polymer surface have been performed by means of in situ atomic force microscopy. The sensor signal change, which reflects the progress of degradation, indicates an accelerated degradation in the presence of the enzyme compared to hydrolysis in neutral pH buffer media. The degradation rate increases with increasing enzyme concentration. The obtained results demonstrate the potential of PMEIS sensors as a very promising tool for in situ and real-time monitoring of degradation of polymers.
The Saturnian moon Enceladus with its extensive water bodies underneath a thick ice sheet cover is a potential candidate for extraterrestrial life. Direct exploration of such extraterrestrial aquatic ecosystems requires advanced access and sampling technologies with a high level of autonomy. A new technological approach has been developed as part of the collaborative research project Enceladus Explorer (EnEx). The concept is based upon a minimally invasive melting probe called the IceMole. The force-regulated, heater-controlled IceMole is able to travel along a curved trajectory as well as upwards. Hence, it allows maneuvers which may be necessary for obstacle avoidance or target selection. Maneuverability, however, necessitates a sophisticated on-board navigation system capable of autonomous operations. The development of such a navigational system has been the focal part of the EnEx project. The original IceMole has been further developed to include relative positioning based on in-ice attitude determination, acoustic positioning, ultrasonic obstacle and target detection integrated through a high-level sensor fusion. This paper describes the EnEx technology and discusses implications for an actual extraterrestrial mission concept.
In this work, a sensor to evaluate sterilization processes with hydrogen peroxide vapor has been characterized. Experimental, analytical and numerical methods were applied to evaluate and study the sensor behavior. The sensor set-up is based on planar interdigitated electrodes. The interdigitated electrode structure consists of 614 electrode fingers spanning over a total sensing area of 20 mm2. Sensor measurements were conducted with and without microbiological spores as well as after an industrial sterilization protocol. The measurements were verified using an analytical expression based on a first-order elliptical integral. A model based on the finite element method with periodic boundary conditions in two dimensions was developed and utilized to validate the experimental findings.