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Auswahl der Herniennetze nach der “effektiven Porosität” - warum das Gewicht weniger wichtig ist
(2012)
Use of textile structures for reinforcement of pelvic floor structures has to consider mechanical forces to the implant, which are quite different to the tension free conditions of the abdominal wall. Thus, biomechanical analysis of textile devices has to include the impact of strain on stretchability and effective porosity. Prolift® and Prolift + M®, developed for tension free conditions, were tested by measuring stretchability and effective porosity applying mechanical strain. For comparison, we used Dynamesh-PR4®, which was designed for pelvic floor repair to withstand mechanical strain. Prolift® at rest showed moderate porosity with little stretchability but complete loss of effective porosity at strain of 4.9 N/cm. Prolift + M® revealed an increased porosity at rest, but at strain showed high stretchability, with subsequent loss of effective porosity at strain of 2.5 N/cm. Dynamesh PR4® preserved its high porosity even under strain, but as consequence of limited stretchability. Though in tension free conditions Prolift® and Prolift + M® can be considered as large pore class I meshes, application of mechanical strain rapidly lead to collapse of pores. The loss of porosity at mechanical stress can be prevented by constructions with high structural stability. Assessment of porosity under strain was found helpful to define requirements for pelvic floor devices. Clinical studies have to prove whether devices with high porosity as well as high structural stability can improve the patients' outcome.
Im Projekt wurden mit Hilfe zeitaufgeloester optischer Messtechniken Relaxations-Dynamiken von optisch angeregten Ladungstraegern und Hochfrequenzeigenschaften von Hochtemperatursupraleitern untersucht. Oberhalb der Sprungtemperatur wurden die Elektron-Phonon-Kopplungskonstanten fuer YBCO und BSCCO bestimmt. Dabei wurde erstmalig ein direkter Zusammenhang zwischen der Sprungtemperatur und der Kopplungstaerke gefunden. Der Kopplungsmechanismus enthaelt sowohl phononische als auch elektronische (spindynamische) Anteile. Unterhalb von T_c wird die Dynamik durch Aufbrechen und Rekombination von Cooper-Paaren bestimmt. Bei den Arbeiten zu den kohaerenten Phononen wurde ein Modell entwickelt, das das 'Anwerfen' der Phononen und das Amplitudenverhalten unterhalb der Sprungtemperatur erklaert. Als begleitende Untersuchungen wurden breitbandige Hochfrequenz-Messungen vorgenommen. Die Methode erlaubt die Untersuchung von Ladungstraegerdichten und von Streumechanismen. Erstmalig wurde in verspannten YBCO-Duennfilmen eine starke temperaturabhaengige Resonanz-Absorption beobachtet, die als Josephson-Plasmaresonanz an intrinsischen Kontakten identifiziert werden konnte. Die Nutzbarkeit dieser Kontakte fuer Bauelemente wurde durch einen Mikrowellendetektor demonstriert. Durch den Nachweis von emittierter gepulster Strahlung aus einer stromdurchflossenen supraleitenden Bruecke nach optischer Anregung wurde erstmals die Einsatzmoeglichkeit von HTSL fuer schnelle optische Schalter demonstriert. Es wurde gezeigt, dass die Schaltgeschwindigkeit eine direkte Folge der Ladungstraegerdynamik ist.
The adoption of the Digital Health Transformation is a tremendous paradigm change in health organizations, which is not a trivial process in reality. For that reason, in this chapter, it is proposed a methodology with the objective to generate a changing culture in healthcare organisations. Such a change culture is essential for the successful implementation of any supporting methods like Interactive Process Mining. It needs to incorporate (mostly) new ways of team-based and evidence-based approaches for solving structural problems in a digital healthcare environment.
Communication via serial bus systems, like CAN, plays an important role for all kinds of embedded electronic and mechatronic systems. To cope up with the requirements for functional safety of safety-critical applications, there is a need to enhance the safety features of the communication systems. One measure to achieve a more robust communication is to add redundant data transmission path to the applications. In general, the communication of real-time embedded systems like automotive applications is tethered, and the redundant data transmission lines are also tethered, increasing the size of the wiring harness and the weight of the system. A radio link is preferred as a redundant transmission line as it uses a complementary transmission medium compared to the wired solution and in addition reduces wiring harness size and weight. Standard wireless links like Wi-Fi or Bluetooth cannot meet the requirements for real-time capability with regard to bus communication. Using the new dual-mode radio enables a redundant transmission line meeting all requirements with regard to real-time capability, robustness and transparency for the data bus. In addition, it provides a complementary transmission medium with regard to commonly used tethered links. A CAN bus system is used to demonstrate the redundant data transfer via tethered and wireless CAN.