Conference Proceeding
Refine
Year of publication
Document Type
- Conference Proceeding (1620) (remove)
Language
- English (1146)
- German (472)
- Multiple languages (1)
- Spanish (1)
Keywords
- Biosensor (25)
- Blitzschutz (15)
- CAD (11)
- Finite-Elemente-Methode (11)
- civil engineering (11)
- Bauingenieurwesen (10)
- Lightning protection (9)
- Einspielen <Werkstoff> (6)
- Telekommunikationsmarkt (6)
- shakedown analysis (6)
- Enterprise Architecture (5)
- Gamification (5)
- Graduiertentagung (5)
- Leadership (5)
- Clusterion (4)
- Energy storage (4)
- Führung (4)
- Kanalisation (4)
- Limit analysis (4)
- Natural language processing (4)
Institute
- Fachbereich Elektrotechnik und Informationstechnik (296)
- Fachbereich Energietechnik (259)
- Fachbereich Medizintechnik und Technomathematik (239)
- Fachbereich Maschinenbau und Mechatronik (207)
- Fachbereich Luft- und Raumfahrttechnik (203)
- Solar-Institut Jülich (167)
- IfB - Institut für Bioengineering (151)
- Fachbereich Bauingenieurwesen (137)
- Fachbereich Wirtschaftswissenschaften (68)
- ECSM European Center for Sustainable Mobility (57)
- INB - Institut für Nano- und Biotechnologien (52)
- MASKOR Institut für Mobile Autonome Systeme und Kognitive Robotik (48)
- Fachbereich Chemie und Biotechnologie (34)
- Nowum-Energy (22)
- Kommission für Forschung und Entwicklung (16)
- Fachbereich Architektur (13)
- ZHQ - Bereich Hochschuldidaktik und Evaluation (10)
- FH Aachen (7)
- Fachbereich Gestaltung (4)
- IaAM - Institut für angewandte Automation und Mechatronik (3)
- Institut fuer Angewandte Polymerchemie (2)
- Verwaltung (2)
- Arbeitsstelle fuer Hochschuldidaktik und Studienberatung (1)
- Digitalisierung in Studium & Lehre (1)
- Freshman Institute (1)
The future of industrial manufacturing and production will increasingly manifest in the form of cyber-physical production systems. Here, Digital Shadows will act as mediators between the physical and digital world to model and operationalize the interactions and relationships between different entities in production systems. Until now, the associated concepts have been primarily pursued and implemented from a technocentric perspective, in which human actors play a subordinate role, if they are considered at all. This paper outlines an anthropocentric approach that explicitly considers the characteristics, behavior, and traits and states of human actors in socio-technical production systems. For this purpose, we discuss the potentials and the expected challenges and threats of creating and using Human Digital Shadows in production.
Modenfilter als Schalldämpfer für axiale Turbomaschinen : Möglichkeiten und Grenzen des Einsatzes
(1992)
Human induced pluripotent stem cells (hiPSCs) have shown to be promising in disease studies and drug screenings [1]. Cardiomyocytes derived from hiPSCs have been extensively investigated using patch-clamping and optical methods to compare their electromechanical behaviour relative to fully matured adult cells. Mathematical models can be used for translating findings on hiPSCCMs to adult cells [2] or to better understand the mechanisms of various ion channels when a drug is applied [3,4]. Paci et al. (2013) [3] developed the first model of hiPSC-CMs, which they later refined based on new data [3]. The model is based on iCells® (Fujifilm Cellular Dynamics, Inc. (FCDI), Madison WI, USA) but major differences among several cell lines and even within a single cell line have been found and motivate an approach for creating sample-specific models. We have developed an optimisation algorithm that parameterises the conductances (in S/F=Siemens/Farad) of the latest Paci et al. model (2018) [5] using current-voltage data obtained in individual patch-clamp experiments derived from an automated patch clamp system (Patchliner, Nanion Technologies GmbH, Munich).