Refine
Year of publication
- 2018 (259) (remove)
Institute
- Fachbereich Medizintechnik und Technomathematik (68)
- Fachbereich Elektrotechnik und Informationstechnik (44)
- IfB - Institut für Bioengineering (41)
- INB - Institut für Nano- und Biotechnologien (25)
- Fachbereich Luft- und Raumfahrttechnik (24)
- Fachbereich Maschinenbau und Mechatronik (24)
- Fachbereich Chemie und Biotechnologie (22)
- Fachbereich Energietechnik (22)
- Fachbereich Wirtschaftswissenschaften (20)
- Fachbereich Bauingenieurwesen (16)
Document Type
- Article (125)
- Conference Proceeding (77)
- Part of a Book (31)
- Book (12)
- Working Paper (3)
- Conference: Meeting Abstract (2)
- Doctoral Thesis (2)
- Patent (2)
- Part of a Periodical (2)
- Conference Poster (1)
Keywords
- Datenschutz (2)
- Digitale Transformation (2)
- Energy efficiency (2)
- Engineering optimization (2)
- Literaturanalyse (2)
- MINLP (2)
- Pump System (2)
- Serious Game (2)
- Water (2)
- Agility (1)
- Antarctica (1)
- Awareness (1)
- Bahadur efficiency (1)
- Bioeconomy (1)
- Bioethanol (1)
- Biorefinery (1)
- Biorefinery definitions (1)
- Bladder (1)
- Booster Stations (1)
- Buffering Capacity (1)
- CDG (1)
- Chance Constraint (1)
- Chemical imaging (1)
- Cloud Computing (1)
- Coat protein (1)
- Competence Developing Game (1)
- Conductive boundary condition (1)
- Coverage probability (1)
- Cramér-von-Mises statistic (1)
- Datenschutzgrundverordnung (1)
- Datenschutzrecht (1)
- Dry surfaces (1)
- EBSCO Discovery Service (1)
- EU-DS-GVO (1)
- EUDSGVO (1)
- Engineering Application (1)
- Enterprise Architecture (1)
- Enzyme nanocarrier (1)
- Equivalence test (1)
- Field-effect device (1)
- Forschungsprozess (1)
- GOSSAMER-1 (1)
- Geschäftsprozessmanagement (1)
- Global optimization (1)
- Glucose biosensor (1)
- Glucose oxidase (1)
- Goodness-of-fit tests for uniformity (1)
- Growth modelling (1)
- IBM Watson Explorer (1)
- INODIS (1)
- IT-Sicherheit (1)
- Identitätsmanagement (1)
- Informationsgetriebene Geschäftsmodelle (1)
- Integrated empirical distribution (survival) function (1)
- Internet der Dinge (1)
- Introduction (1)
- Inverse scattering (1)
- Jupiter (1)
- Kernel density estimator (1)
- Lab-on-Chip (1)
- Latin Hypercube Sampling (1)
- Length of confidence intervals (1)
- Light-addressable potentiometric sensor (1)
- Lignocellulose feedstook (1)
- Literatur-analyse-prozess (1)
- Literaturdaten (1)
- Literature review (1)
- MASCOT (1)
- Mars (1)
- Mechanical simulation (1)
- Microbial adhesion (1)
- Minimum dissipation (1)
- Mixed-integer nonlinear problem (1)
- Monetarisierung (1)
- Multi-criteria optimization (1)
- Muscle fibers (1)
- Network (1)
- Numerical inversion of Laplace transforms (1)
- Paper recycling (1)
- Passive stretching (1)
- Pelvic floor dysfunction (1)
- Pelvic muscle (1)
- Pitman efficiency (1)
- Planetary exploration (1)
- Player Types (1)
- Potentiometry (1)
- Process engineering (1)
- Process schemes (1)
- Projektbeispiele (1)
- Prozessautomatisierung (1)
- Qualitative Wertschöpfungsanalyse (1)
- RC frames (1)
- Reconstruction (1)
- Rehabilitation Technology and Prosthetics (1)
- Renewable resources (1)
- Research process (1)
- Sampling methods (1)
- Softwareroboter (1)
- Stochastic Programming (1)
- Story (1)
- Surface microorganisms (1)
- Surgical Navigation and Robotics (1)
- Swabbing (1)
- Technische Schutzmaßnahmen (1)
- Text Analytics (1)
- Text Analytics (1)
- Text analytics (1)
- Text mining (1)
- Tobacco mosaic virus (TMV) (1)
- Transition (1)
- Transmission eigenvalues (1)
- Turbulence (1)
- Uncertainty (1)
- Ureter (1)
- Video Game (1)
- Water Distribution (1)
- Water Supply Networks (1)
- Wilcoxon tests (1)
- Wissenstransfer (1)
- achilles tendon (1)
- agile (1)
- business simulation (1)
- design of technical systems (1)
- earthquakes (1)
- energy absorption (1)
- energy dissipation (1)
- frequency mixing (1)
- functional data (1)
- habitability (1)
- huge dimensional data (1)
- ice moons (1)
- icy moons (1)
- in-plane and out-of-plane failure (1)
- legal obligations (1)
- life detection (1)
- magnetic beads (1)
- magnetic sensing (1)
- mathematical optimization (1)
- mechanical buffer (1)
- multiple NEA rendezvous (1)
- optimization (1)
- product liability (1)
- remote sensing (1)
- resilience (1)
- separable Hilbert space (1)
- slum classification (1)
- small spacecraft (1)
- solar sail (1)
- space missions (1)
- stiffness (1)
- superparamagnetic nanoparticles (1)
- tablet game (1)
- underwater vehicle (1)
- water supply design (1)
Motivation-based Learning: Teaching Fundamentals of Electrical Engineering with an LED Spinning Top
(2018)
Impressum | Inhalt 03
Thomas Tünnemann | Unterwegs...am Wege 04
Projekte 06
Annelie Wirtz | Arrivato 08
Sebastian Rupp | Tracce Passate 18
Henri Boh | Terrazze sopra il lago 28
Hermann Stuzmann | L´Ammissione è Gratuita 32
Vivienne Scheidz | IL Potere dei Simboli 34
Felix Keller | Strada Infinita 38
Moran Dorner | Catturato nel Posto 42
Kevin Osterkamp | Vortice 46
Kristina Foidle | La Vespa e il Fico 52
Simon Rix | Sognare Sulla Strada 58
Jennifer Sikora | Strada Pietrosa 66
Sabrina Frömbgen | Bolla di Pensiero 72
Miriam Azzab | Il Momento 78
Georg Mörke | Sentiero stretto 84
Saskia Frömbgen | Nuova Prospetiva 90
Frank Drehsen | A grado a grado 96
Caronlin Grün | Le prospettive 100
Thomas Tünnemann | Flusso nella Foresta 104
Atmosphärisches
Auf die Küche | Kulinarisches 114
Carpe Diem | Fotografisches 116
Many efforts are made worldwide to establish magnetic fluid hyperthermia (MFH) as a treatment for organ-confined tumors. However, translation to clinical application hardly succeeds as it still lacks of understanding the mechanisms determining MFH cytotoxic effects. Here, we investigate the intracellular MFH efficacy with respect to different parameters and assess the intracellular cytotoxic effects in detail. For this, MiaPaCa-2 human pancreatic tumor cells and L929 murine fibroblasts were loaded with iron-oxide magnetic nanoparticles (MNP) and exposed to MFH for either 30 min or 90 min. The resulting cytotoxic effects were assessed via clonogenic assay. Our results demonstrate that cell damage depends not only on the obvious parameters bulk temperature and duration of treatment, but most importantly on cell type and thermal energy deposited per cell during MFH treatment. Tumor cell death of 95% was achieved by depositing an intracellular total thermal energy with about 50% margin to damage of healthy cells. This is attributed to combined intracellular nanoheating and extracellular bulk heating. Tumor cell damage of up to 86% was observed for MFH treatment without perceptible bulk temperature rise. Effective heating decreased by up to 65% after MNP were internalized inside cells.
Magnetic nanoparticles (MNPs) are used as therapeutic and diagnostic agents for local delivery of heat and image contrast enhancement in diseased tissue. Besides magnetization, the most important parameter that determines their performance for these applications is their magnetic relaxation, which can be affected when MNPs immobilize and agglomerate inside tissues. In this letter, we investigate different MNP agglomeration states for their magnetic relaxation properties under excitation in alternating fields and relate this to their heating efficiency and imaging properties. With focus on magnetic fluid hyperthermia, two different trends in MNP heating efficiency are measured: an increase by up to 23% for agglomerated MNP in suspension and a decrease by up to 28% for mixed states of agglomerated and immobilized MNP, which indicates that immobilization is the dominant effect. The same comparatively moderate effects are obtained for the signal amplitude in magnetic particle spectroscopy.
Kinematics and kinetics of handcycling propulsion at increasing workloads in able-bodied subjects
(2018)
In Paralympic sports, biomechanical optimisation of movements and equipment seems to be promising for improving performance. In handcycling, information about the biomechanics of this sport is mainly provided by case studies. The aim of the current study was (1) to examine changes in handcycling propulsion kinematics and kinetics due to increasing workloads and (2) identify parameters that are associated with peak aerobic performance. Twelve non-disabled male competitive triathletes without handcycling experience voluntarily participated in the study. They performed an initial familiarisation protocol and incremental step test until exhaustion in a recumbent racing handcycle that was attached to an ergometer. During the incremental test, tangential crank kinetics, 3D joint kinematics, blood lactate and ratings of perceived exertion (local and global) were identified. As a performance criterion, the maximal power output during the step test (Pmax) was calculated and correlated with biomechanical parameters. For higher workloads, an increase in crank torque was observed that was even more pronounced in the pull phase than in the push phase. Furthermore, participants showed an increase in shoulder internal rotation and abduction and a decrease in elbow flexion and retroversion. These changes were negatively correlated with performance. At high workloads, it seems that power output is more limited by the transition from pull to push phase than at low workloads. It is suggested that successful athletes demonstrate small alterations of their kinematic profile due to increasing workloads. Future studies should replicate and expand the test spectrum (sprint and continuous loads) as well as use methods like surface electromyography (sEMG) with elite handcyclists.
Impaired cerebral autoregulation and neurovascular coupling (NVC) contribute to delayed cerebral ischemia after subarachnoid hemorrhage (SAH). Retinal vessel analysis (RVA) allows non-invasive assessment of vessel dimension and NVC hereby demonstrating a predictive value in the context of various neurovascular diseases. Using RVA as a translational approach, we aimed to assess the retinal vessels in patients with SAH. RVA was performed prospectively in 24 patients with acute SAH (group A: day 5–14), in 11 patients 3 months after ictus (group B: day 90 ± 35), and in 35 age-matched healthy controls (group C). Data was acquired using a Retinal Vessel Analyzer (Imedos Systems UG, Jena) for examination of retinal vessel dimension and NVC using flicker-light excitation. Diameter of retinal vessels—central retinal arteriolar and venular equivalent—was significantly reduced in the acute phase (p < 0.001) with gradual improvement in group B (p < 0.05). Arterial NVC of group A was significantly impaired with diminished dilatation (p < 0.001) and reduced area under the curve (p < 0.01) when compared to group C. Group B showed persistent prolonged latency of arterial dilation (p < 0.05). Venous NVC was significantly delayed after SAH compared to group C (A p < 0.001; B p < 0.05). To our knowledge, this is the first clinical study to document retinal vasoconstriction and impairment of NVC in patients with SAH. Using non-invasive RVA as a translational approach, characteristic patterns of compromise were detected for the arterial and venous compartment of the neurovascular unit in a time-dependent fashion. Recruitment will continue to facilitate a correlation analysis with clinical course and outcome.