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Niemand kann der täglichen Erfahrung mit Haaren entfliehen. Ob es nun der eigene Blick in den Spiegel ist, die Begegnung mit anderen Menschen, oder die mit Testimonials gespeiste Werbung für diverse Haarprodukte. Haare gehören zum Alltag. Aber was steckt hinter dem Haar, wenn es denn einmal von uns und unserer Person getrennt wird und nur noch als körperloses Büschel erkennbar ist? Zum Beispiel in Form von Echthaarextensions. Wer bedient freiwillig und unfreiwillig durch die eigene Haarpracht die millionenschwere Echthaarindustrie? Wer profitiert von der haarigen Ware und wer sind die Käufer, die den globalen Handel vorantreiben? Das jährlich erscheinende Bookazine TRICHOTOMY geht diesen Fragestellungen auf den Grund. Investigative Artikel enthüllen die Produktion und Ökonomie der vorwiegend anonymisierten Echthaarindustrie und porträtieren die Menschen und Schicksale 'hinter den Haaren'.
Was ist „Männlichkeit“ und was verstehen junge Erwachsene unter diesem Begriff? Das Ziel des Projektes war 18 bis 30 jährige Jungen und Männer des biologisch männlichen Geschlechts zu befragen, was ihre Definition von Männlichkeit sei. Diese Arbeit hatte die Intention den Befragten einen sicheren Raum zu geben, damit sie ihre ehrlichen Antworten äußern und ihre wahren Gesichter zeigen können. Die dabei entstandenen Fotografien sollen die Persönlichkeiten und die seelische Verfassung der abgebildeten Personen widerspiegeln. Es handelt sich um eine soziologische Bestandsaufnahme der „Männlichkeiten“ der heutigen Jugend und der heranwachsenden Erwachsenen im 21. Jahrhundert.
Eine Kampagne, die darauf ausgerichtet ist, die Bevölkerung auf sozialer Ebene aufzurufen, Impf-Skeptiker aufzuklären und von Impfungen zu überzeugen. Anhand von offiziellen Statistiken, die optisch ansprechend aufbereitet wurden, werden die Menschen über Krankheiten und dazu gehörige Risiken informiert. Des Weiteren wird der Impferfolg grafisch dokumentiert und leicht verständlich präsentiert, ohne Fakten auszulassen.
Durch eine Serie Plakate verschiedener Formate werden die Betrachter animiert, die Homepage impfen.info aufzusuchen und das reichhaltige Informationsangebot zu nutzen.
Mithilfe einer amüsanten Postkartenreihe wird die Verbreitung von Krankheitserregern simuliert und postalisch in die Haushalte der Impfgegner- und Skeptiker gebracht, um zu verdeutlichen, wie rasant Viren sich verbreiten und wie wichtig es ist, sich und seine Lieben zu schützen.
Adapting Augmented Reality Systems to the users’ needs using Gamification and error solving methods
(2021)
Animations of virtual items in AR support systems are typically predefined and lack interactions with dynamic physical environments. AR applications rarely consider users’ preferences and do not provide customized spontaneous support under unknown situations. This research focuses on developing adaptive, error-tolerant AR systems based on directed acyclic graphs and error resolving strategies. Using this approach, users will have more freedom of choice during AR supported work, which leads to more efficient workflows. Error correction methods based on CAD models and predefined process data create individual support possibilities. The framework is implemented in the Industry 4.0 model factory at FH Aachen.
The course Physics for Electrical Engineering is part of the curriculum of the
bachelor program Electrical Engineering at University of Applied Science Aachen.
Before covid-19 the course was conducted in a rather traditional way with all parts
(lecture, exercise and lab) face-to-face. This teaching approach changed
fundamentally within a week when the covid-19 limitations forced all courses to
distance learning. All parts of the course were transformed to pure distance learning
including synchronous and asynchronous parts for the lecture, live online-sessions
for the exercises and self-paced labs at home. Using these methods, the course was
able to impart the required knowledge and competencies. Taking the teacher’s
observations of the student’s learning behaviour and engagement, the formal and
informal feedback of the students and the results of the exams into account, the new
methods are evaluated with respect to effectiveness, sustainability and suitability for
competence transfer. Based on this analysis strong and weak points of the concept
and countermeasures to solve the weak points were identified. The analysis further
leads to a sustainable teaching approach combining synchronous and asynchronous
parts with self-paced learning times that can be used in a very flexible manner for
different learning scenarios, pure online, hybrid (mixture of online and presence
times) and pure presence teaching.
The transition within transportation towards battery electric vehicles can lead to a more sustainable future. To account for the development goal ‘climate action’ stated by the United Nations, it is mandatory, within the conceptual design phase, to derive energy-efficient system designs. One barrier is the uncertainty of the driving behaviour within the usage phase. This uncertainty is often addressed by using a stochastic synthesis process to derive representative driving cycles and by using cycle-based optimization. To deal with this uncertainty, a new approach based on a stochastic optimization program is presented. This leads to an optimization model that is solved with an exact solver. It is compared to a system design approach based on driving cycles and a genetic algorithm solver. Both approaches are applied to find efficient electric powertrains with fixed-speed and multi-speed transmissions. Hence, the similarities, differences and respective advantages of each optimization procedure are discussed.
Geochemical characterisation of hypersaline waters is difficult as high concentrations of salts hinder the analysis of constituents at low concentrations, such as trace metals, and the collection of samples for trace metal analysis in natural waters can be easily contaminated. This is particularly the case if samples are collected by non-conventional techniques such as those required for aquatic subglacial environments. In this paper we present the first analysis of a subglacial brine from Taylor Valley, (~ 78°S), Antarctica for the trace metals: Ba, Co, Mo, Rb, Sr, V, and U. Samples were collected englacially using an electrothermal melting probe called the IceMole. This probe uses differential heating of a copper head as well as the probe’s sidewalls and an ice screw at the melting head to move through glacier ice. Detailed blanks, meltwater, and subglacial brine samples were collected to evaluate the impact of the IceMole and the borehole pump, the melting and collection process, filtration, and storage on the geochemistry of the samples collected by this device. Comparisons between melt water profiles through the glacier ice and blank analysis, with published studies on ice geochemistry, suggest the potential for minor contributions of some species Rb, As, Co, Mn, Ni, NH4+, and NO2−+NO3− from the IceMole. The ability to conduct detailed chemical analyses of subglacial fluids collected with melting probes is critical for the future exploration of the hundreds of deep subglacial lakes in Antarctica.
Dieses Lehrbuch vermittelt die Grundlagen der Wärmeübertragung sowie den Umgang mit EXCEL-VBA von der Erstellung von Makros bis zu benutzerdefinierten Funktionen. Es legt damit eine Basis für die schnelle und professionelle Durchführung von Berechnungen und Simulationen. Die angeleitete Erstellung von Berechnungsmodulen mit EXCEL und VBA aus allen wichtigen Bereichen der Wärmeübertragung bildet den inhaltlichen Schwerpunkt. Dazu zählen die stationäre Wärmeleitung und der stationäre Wärmedurchgang, die instationäre Wärmeleitung, der Wärmeübergang bei freier und erzwungener Konvektion sowie die Wärmestrahlung und der Wärmeübergang beim Kondensieren und Sieden. Soweit sinnvoll und möglich werden die Stoffwertekorrelationen und die Berechnungsvorschriften aus dem VDI-Wärmeatlas verwendet. Für ausgewählte Anwendungen werden zudem komplexere Auslegungen und Simulationen von Prozessen der Wärmeübertragung sowie von Wärmeübertragern erstellt. Die Zielgruppen: Studierende in Bachelor- und Masterstudiengängen, Praktiker im Engineering
This book provides a compact introduction to the bootstrap method. In addition to classical results on point estimation and test theory, multivariate linear regression models and generalized linear models are covered in detail. Special attention is given to the use of bootstrap procedures to perform goodness-of-fit tests to validate model or distributional assumptions. In some cases, new methods are presented here for the first time.
The text is motivated by practical examples and the implementations of the corresponding algorithms are always given directly in R in a comprehensible form. Overall, R is given great importance throughout. Each chapter includes a section of exercises and, for the more mathematically inclined readers, concludes with rigorous proofs. The intended audience is graduate students who already have a prior knowledge of probability theory and mathematical statistics.
Communication via serial bus systems, like CAN, plays an important role for all kinds of embedded electronic and mechatronic systems. To cope up with the requirements for functional safety of safety-critical applications, there is a need to enhance the safety features of the communication systems. One measure to achieve a more robust communication is to add redundant data transmission path to the applications. In general, the communication of real-time embedded systems like automotive applications is tethered, and the redundant data transmission lines are also tethered, increasing the size of the wiring harness and the weight of the system. A radio link is preferred as a redundant transmission line as it uses a complementary transmission medium compared to the wired solution and in addition reduces wiring harness size and weight. Standard wireless links like Wi-Fi or Bluetooth cannot meet the requirements for real-time capability with regard to bus communication. Using the new dual-mode radio enables a redundant transmission line meeting all requirements with regard to real-time capability, robustness and transparency for the data bus. In addition, it provides a complementary transmission medium with regard to commonly used tethered links. A CAN bus system is used to demonstrate the redundant data transfer via tethered and wireless CAN.
Multi-attribute relation extraction (MARE): simplifying the application of relation extraction
(2021)
Natural language understanding’s relation extraction makes innovative and encouraging novel business concepts possible and facilitates new digitilized decision-making processes. Current approaches allow the extraction of relations with a fixed number of entities as attributes. Extracting relations with an arbitrary amount of attributes requires complex systems and costly relation-trigger annotations to assist these systems. We introduce multi-attribute relation extraction (MARE) as an assumption-less problem formulation with two approaches, facilitating an explicit mapping from business use cases to the data annotations. Avoiding elaborated annotation constraints simplifies the application of relation extraction approaches. The evaluation compares our models to current state-of-the-art event extraction and binary relation extraction methods. Our approaches show improvement compared to these on the extraction of general multi-attribute relations.
Conventional EEG devices cannot be used in everyday life and
hence, past decade research has been focused on Ear-EEG for mobile,
at-home monitoring for various applications ranging from
emotion detection to sleep monitoring. As the area available for
electrode contact in the ear is limited, the electrode size and location
play a vital role for an Ear-EEG system. In this investigation, we
present a quantitative study of ear-electrodes with two electrode
sizes at different locations in a wet and dry configuration. Electrode
impedance scales inversely with size and ranges from 450 kΩ to
1.29 MΩ for dry and from 22 kΩ to 42 kΩ for wet contact at 10 Hz.
For any size, the location in the ear canal with the lowest impedance
is ELE (Left Ear Superior), presumably due to increased contact
pressure caused by the outer-ear anatomy. The results can be used
to optimize signal pickup and SNR for specific applications. We
demonstrate this by recording sleep spindles during sleep onset
with high quality (5.27 μVrms).
The fourth industrial revolution introduces disruptive technologies to production environments. One of these technologies are multi-agent systems (MASs), where agents virtualize machines. However, the agent's actual performances in production environments can hardly be estimated as most research has been focusing on isolated projects and specific scenarios. We address this gap by implementing a highly connected and configurable reference model with quantifiable key performance indicators (KPIs) for production scheduling and routing in single-piece workflows. Furthermore, we propose an algorithm to optimize the search of extrema in highly connected distributed systems. The benefits, limits, and drawbacks of MASs and their performances are evaluated extensively by event-based simulations against the introduced model, which acts as a benchmark. Even though the performance of the proposed MAS is, on average, slightly lower than the reference system, the increased flexibility allows it to find new solutions and deliver improved factory-planning outcomes. Our MAS shows an emerging behavior by using flexible production techniques to correct errors and compensate for bottlenecks. This increased flexibility offers substantial improvement potential. The general model in this paper allows the transfer of the results to estimate real systems or other models.
Dieser "Crashkurs" eignet sich ausgezeichnet für die kompakte Wiederholung und die zielgerichtete Prüfungsvorbereitung. Das Buch ist aufgrund seiner fallbezogenen Ausrichtung vor allem für Anfänger gedacht, eignet sich aber auch für fortgeschrittene Studierende zur kompakten Wiederholung. Einfache Merksätze, Fälle, Übersichten, Definitionen und kurze Zusammenfassungen lassen sich leicht einprägen und geben Sicherheit für die Prüfung. Vorteile auf einen Blick: Das wichtigste BGB-Know-how als Repetitorium vor der Prüfung, mit erprobten Merksätzen und kurzen Zusammenfassungen,
Fall für Fall sicher durch die Prüfung
Kleidung ist ein Kommunikationsmedium. Im Projekt wird Bekleidung als Informationsträger genutzt, um über die verschiedenen Abschnitte im Zyklus eines Kleidungsstücks sowie die Missstände in der Bekleidungsindustrie zu informieren. Entstanden sind 6 Kleidungsstücke, jeweils eins pro Abschnitt im Zyklus, vom Baumwollanbau über Spinnereien, Produktionsfabriken, dem Einzelhandel und Gebrauch bis zur Entsorgung.
Die einfach gehaltenen Kleidungsstücke besitzen Aufdrucke. Über eine Augmented-Reality-App können die Kleidungsstücke gescannt werden. In Kombination mit der digitalen Ebene werden die Aufdrucke zu Informationsgrafiken. So wird unter anderem über die grausamen Arbeitsumstände in der Produktion informiert oder darüber, dass wir unsere Kleidungsstücke durchschnittlich nur 4x anziehen. Immer geht es darum, den Betrachter dazu anzuregen, seine Konsumentscheidungen zu überdenken.
The progress in natural language processing (NLP) research over the last years, offers novel business opportunities for companies, as automated user interaction or improved data analysis. Building sophisticated NLP applications requires dealing with modern machine learning (ML) technologies, which impedes enterprises from establishing successful NLP projects. Our experience in applied NLP research projects shows that the continuous integration of research prototypes in production-like environments with quality assurance builds trust in the software and shows convenience and usefulness regarding the business goal. We introduce STAMP 4 NLP as an iterative and incremental process model for developing NLP applications. With STAMP 4 NLP, we merge software engineering principles with best practices from data science. Instantiating our process model allows efficiently creating prototypes by utilizing templates, conventions, and implementations, enabling developers and data scientists to focus on the business goals. Due to our iterative-incremental approach, businesses can deploy an enhanced version of the prototype to their software environment after every iteration, maximizing potential business value and trust early and avoiding the cost of successful yet never deployed experiments.
The integration of frequently changing, volatile product data from different manufacturers into a single catalog is a significant challenge for small and medium-sized e-commerce companies. They rely on timely integrating product data to present them aggregated in an online shop without knowing format specifications, concept understanding of manufacturers, and data quality. Furthermore, format, concepts, and data quality may change at any time. Consequently, integrating product catalogs into a single standardized catalog is often a laborious manual task. Current strategies to streamline or automate catalog integration use techniques based on machine learning, word vectorization, or semantic similarity. However, most approaches struggle with low-quality or real-world data. We propose Attribute Label Ranking (ALR) as a recommendation engine to simplify the integration process of previously unknown, proprietary tabular format into a standardized catalog for practitioners. We evaluate ALR by focusing on the impact of different neural network architectures, language features, and semantic similarity. Additionally, we consider metrics for industrial application and present the impact of ALR in production and its limitations.
For now, the Planetary Defense Conference Exercise 2021's incoming fictitious(!), asteroid, 2021 PDC, seems headed for impact on October 20th, 2021, exactly 6 months after its discovery. Today (April 26th, 2021), the impact probability is 5%, in a steep rise from 1 in 2500 upon discovery six days ago. We all know how these things end. Or do we? Unless somebody kicked off another headline-grabbing media scare or wants to keep civil defense very idle very soon, chances are that it will hit (note: this is an exercise!). Taking stock, it is barely 6 months to impact, a steadily rising likelihood that it will actually happen, and a huge uncertainty of possible impact energies: First estimates range from 1.2 MtTNT to 13 GtTNT, and this is not even the worst-worst case: a 700 m diameter massive NiFe asteroid (covered by a thin veneer of Ryugu-black rubble to match size and brightness), would come in at 70 GtTNT. In down to Earth terms, this could be all between smashing fireworks over some remote area of the globe and a 7.5 km crater downtown somewhere. Considering the deliberate and sedate ways of development of interplanetary missions it seems we can only stand and stare until we know well enough where to tell people to pack up all that can be moved at all and save themselves. But then, it could just as well be a smaller bright rock. The best estimate is 120 m diameter from optical observation alone, by 13% standard albedo. NASA's upcoming DART mission to binary asteroid (65803) Didymos is designed to hit such a small target, its moonlet Dimorphos. The Deep Impact mission's impactor in 2005 successfully guided itself to the brightest spot on comet 9P/Tempel 1, a relatively small feature on the 6 km nucleus. And 'space' has changed: By the end of this decade, one satellite communication network plans to have launched over 11000 satellites at a pace of 60 per launch every other week. This level of series production is comparable in numbers to the most prolific commercial airliners. Launch vehicle production has not simply increased correspondingly – they can be reused, although in a trade for performance. Optical and radio astronomy as well as planetary radar have made great strides in the past decade, and so has the design and production capability for everyday 'high-tech' products. 60 years ago, spaceflight was invented from scratch within two years, and there are recent examples of fast-paced space projects as well as a drive towards 'responsive space'. It seems it is not quite yet time to abandon all hope. We present what could be done and what is too close to call once thinking is shoved out of the box by a clear and present danger, to show where a little more preparedness or routine would come in handy – or become decisive. And if we fail, let's stand and stare safely and well instrumented anywhere on Earth together in the greatest adventure of science.
Digital Shadows as the aggregation, linkage and abstraction of data relating to physical objects are a central vision for the future of production. However, the majority of current research takes a technocentric approach, in which the human actors in production play a minor role. Here, the authors present an alternative anthropocentric perspective that highlights the potential and main challenges of extending the concept of Digital Shadows to humans. Following future research methodology, three prospections that illustrate use cases for Human Digital Shadows across organizational and hierarchical levels are developed: human-robot collaboration for manual work, decision support and work organization, as well as human resource management. Potentials and challenges are identified using separate SWOT analyses for the three prospections and common themes are emphasized in a concluding discussion.
The feasibility of light-addressed detection and manipulation of pH gradients inside an electrochemical microfluidic cell was studied. Local pH changes, induced by a light-addressable electrode (LAE), were detected using a light-addressable potentiometric sensor (LAPS) with different measurement modes representing an actuator-sensor system. Biosensor functionality was examined depending on locally induced pH gradients with the help of the model enzyme penicillinase, which had been immobilized in the microfluidic channel. The surface morphology of the LAE and enzyme-functionalized LAPS was studied by scanning electron microscopy. Furthermore, the penicillin sensitivity of the LAPS inside the microfluidic channel was determined with regard to the analyte’s pH influence on the enzymatic reaction rate. In a final experiment, the LAE-controlled pH inhibition of the enzyme activity was monitored by the LAPS.
Past earthquakes demonstrated the high vulnerability of industrial facilities equipped with complex process technologies leading to serious damage of the process equipment and multiple and simultaneous release of hazardous substances in industrial facilities. Nevertheless, the design of industrial plants is inadequately described in recent codes and guidelines, as they do not consider the dynamic interaction between the structure and the installations and thus the effect of seismic response of the installations on the response of the structure and vice versa. The current code-based approach for the seismic design of industrial facilities is considered not enough for ensure proper safety conditions against exceptional event entailing loss of content and related consequences. Accordingly, SPIF project (Seismic Performance of Multi- Component Systems in Special Risk Industrial Facilities) was proposed within the framework of the European H2020 - SERA funding scheme (Seismology and Earthquake Engineering Research Infrastructure Alliance for Europe). The objective of the SPIF project is the investigation of the seismic behavior of a representative industrial structure equipped with complex process technology by means of shaking table tests. The test structure is a three-story moment resisting steel frame with vertical and horizontal vessels and cabinets, arranged on the three levels and connected by pipes. The dynamic behavior of the test structure and installations is investigated with and without base isolation. Furthermore, both firmly anchored and isolated components are taken into account to compare their dynamic behavior and interactions with each other. Artificial and synthetic ground motions are applied to study the seismic response at different PGA levels. After each test, dynamic identification measurements are carried out to characterize the system condition. The contribution presents the numerical simulations to calibrate the tests on the prototype, the experimental setup of the investigated structure and installations, selected measurement data and finally describes preliminary experimental results.
Development of open educational resources for renewable energy and the energy transition process
(2021)
The dissemination of knowledge about renewable energies is understood as a social task with the highest topicality. The transfer of teaching content on renewable energies into digital open educational resources offers the opportunity to significantly accelerate the implementation of the energy transition. Thus, in the here presented project six German universities create open educational resources for the energy transition. These materials are available to the public on the internet under a free license. So far there has been no publicly accessible, editable media that cover entire learning units about renewable energies extensively and in high technical quality. Thus, in this project, the content that remains up-to-date for a longer period is appropriately prepared in terms of media didactics. The materials enable lecturers to provide students with in-depth training about technologies for the energy transition. In a particular way, the created material is also suitable for making the general public knowledgeable about the energy transition with scientifically based material.
7T MR Safety
(2021)
Die ästhetische Tonalität des Jazz : Immersion durch 3D-Visualisierung und musikalische Interaktion
(2021)
Das Ausstellungskonzept »Free Jazz: A Collective Improvisation« widmet sich der ästhetischen Tonalität des gleichnamigen Albums von Ornette Coleman. Das besagte Album bildete den Grundstein für die Etablierung des Free Jazz – einer Musikform, die sich durch ihre schrille, hierarchiefreie Klangwelt sowie ein freies Improvisationsspiel auszeichnet und mit den gängigen Konventionen des Jazz bricht. Zu jedem der 8 Musiker, welche gemeinsam das von Coleman zusammengestellte Doppelquartett ergeben, wurden individuell abgestimmte, animierte und interaktive 3D-Gebilde konzipiert. Diese reagieren auf den Sound der jeweiligen Instrumente sowie die Position der Besuchenden und ermöglichen einen audiovisuellen, immersiven Zugang zum Album. Die Interaktion zwischen dem Publikum und den Gebilden schafft Raum für eine kollektive Improvisation auf sowohl der visuellen als auch auditiven Ebene.
Eigenkapitalkosten sind eine wesentliche Determinante bei der Wertbestimmung von Unternehmen und Unternehmensteilen. Die Eigenkapitalkosten werden regelmäßig mittels des CAPM bestimmt. Für sog. konzerninterne Routinefunktionen mit geringem Risiko stellt diese Bestimmung mittels CAPM ein Problem dar, da börsennotierte Peergroups für eine zuverlässige Bestimmung des Beta-Faktors meist nicht identifizierbar sind. Damit ergeben sich bei Bewertungen von Routineunternehmen Unsicherheiten und Konfliktpotenzial in steuerlichen Betriebsprüfungen. Dieser Beitrag gibt einen Überblick der in der Praxis genutzten Ansätze und stellt eine theoretische Fundierung zur Bestimmung der Eigenkapitalkosten von konzerninternen Routinefunktionen vor. Dabei wird verdeutlicht, dass Eigenkapitalkosten von konzerninternen Routinefunktionen nicht denen des Gesamtkonzerns entsprechen und Praktikeransätze eine grundsätzliche Berechtigung besitzen.
Biologically sensitive field-effect devices (BioFEDs) advantageously combine the electronic field-effect functionality with the (bio)chemical receptor’s recognition ability for (bio)chemical sensing. In this review, basic and widely applied device concepts of silicon-based BioFEDs (ion-sensitive field-effect transistor, silicon nanowire transistor, electrolyte-insulator-semiconductor capacitor, light-addressable potentiometric sensor) are presented and recent progress (from 2019 to early 2021) is discussed. One of the main advantages of BioFEDs is the label-free sensing principle enabling to detect a large variety of biomolecules and bioparticles by their intrinsic charge. The review encompasses applications of BioFEDs for the label-free electrical detection of clinically relevant protein biomarkers, deoxyribonucleic acid molecules and viruses, enzyme-substrate reactions as well as recording of the cell acidification rate (as an indicator of cellular metabolism) and the extracellular potential.
Cardiopulmonary bypass (CPB) is a standard technique for cardiac surgery, but comes with the risk of severe neurological complications (e.g. stroke) caused by embolisms and/or reduced cerebral perfusion. We report on an aortic cannula prototype design (optiCAN) with helical outflow and jet-splitting dispersion tip that could reduce the risk of embolic events and restores cerebral perfusion to 97.5% of physiological flow during CPB in vivo, whereas a commercial curved-tip cannula yields 74.6%. In further in vitro comparison, pressure loss and hemolysis parameters of optiCAN remain unaffected. Results are reproducibly confirmed in silico for an exemplary human aortic anatomy via computational fluid dynamics (CFD) simulations. Based on CFD simulations, we firstly show that optiCAN design improves aortic root washout, which reduces the risk of thromboembolism. Secondly, we identify regions of the aortic intima with increased risk of plaque release by correlating areas of enhanced plaque growth and high wall shear stresses (WSS). From this we propose another easy-to-manufacture cannula design (opti2CAN) that decreases areas burdened by high WSS, while preserving physiological cerebral flow and favorable hemodynamics. With this novel cannula design, we propose a cannulation option to reduce neurological complications and the prevalence of stroke in high-risk patients after CPB.
Aneurysmal subarachnoid hemorrhage (aSAH) is associated with early and delayed brain injury due to several underlying and interrelated processes, which include inflammation, oxidative stress, endothelial, and neuronal apoptosis. Treatment with melatonin, a cytoprotective neurohormone with anti-inflammatory, anti-oxidant and anti-apoptotic effects, has been shown to attenuate early brain injury (EBI) and to prevent delayed cerebral vasospasm in experimental aSAH models. Less is known about the role of endogenous melatonin for aSAH outcome and how its production is altered by the pathophysiological cascades initiated during EBI. In the present observational study, we analyzed changes in melatonin levels during the first three weeks after aSAH.
Thrombogenic complications are a main issue in mechanical circulatory support (MCS). There is no validated in vitro method available to quantitatively assess the thrombogenic performance of pulsatile MCS devices under realistic hemodynamic conditions. The aim of this study is to propose a method to evaluate the thrombogenic potential of new designs without the use of complex in-vivo trials. This study presents a novel in vitro method for reproducible thrombogenicity testing of pulsatile MCS systems using low molecular weight heparinized porcine blood. Blood parameters are continuously measured with full blood thromboelastometry (ROTEM; EXTEM, FIBTEM and a custom-made analysis HEPNATEM). Thrombus formation is optically observed after four hours of testing. The results of three experiments are presented each with two parallel loops. The area of thrombus formation inside the MCS device was reproducible. The implantation of a filter inside the loop catches embolizing thrombi without a measurable increase of platelet activation, allowing conclusions of the place of origin of thrombi inside the device. EXTEM and FIBTEM parameters such as clotting velocity (α) and maximum clot firmness (MCF) show a total decrease by around 6% with a characteristic kink after 180 minutes. HEPNATEM α and MCF rise within the first 180 minutes indicate a continuously increasing activation level of coagulation. After 180 minutes, the consumption of clotting factors prevails, resulting in a decrease of α and MCF. With the designed mock loop and the presented protocol we are able to identify thrombogenic hot spots inside a pulsatile pump and characterize their thrombogenic potential.
A new formulation to calculate the shakedown limit load of Kirchhoff plates under stochastic conditions of strength is developed. Direct structural reliability design by chance con-strained programming is based on the prescribed failure probabilities, which is an effective approach of stochastic programming if it can be formulated as an equivalent deterministic optimization problem. We restrict uncertainty to strength, the loading is still deterministic. A new formulation is derived in case of random strength with lognormal distribution. Upper bound and lower bound shakedown load factors are calculated simultaneously by a dual algorithm.
Neuerfindung der Ligaturen
(2021)
Gegenstand des Projekts ist, Ligaturen als erweiterte Mittel der Informationsübertragung einzusetzen.
Ligaturen als zusätzliches Instrument sollen die visuelle Komponente des Textes unterstützen, ihm die gewisse Frische einhauchen und ihn hiermit insgesamt sichtbarer, origineller und moderner machen. Der Einsatzbereich erstreckt sich hierbei in die verschiedensten Bereiche hin über Design und Werbung, als auch im Handel oder in sozialen Bereichen.
Hierbei kann eine große Anzahl an Wörtern neue Formen annehmen und mithin an neuem Leben und Bedeutung gewinnen, was sicherlich die allgemeinen Sprachmittel bereichern wird.
Auf einer historischen Basis und mit Hilfe der Dekonstruktion wurden neue Formen der Ligaturen geschaffen — seltsame, kontroverse, auffällige und einzigartige.
DO or DIE: Leistungssport
(2021)
Es ist dieser eine Moment, der über Versagen oder Erfolg entscheidet. Dieser Augenblick, der so unfassbar wichtig ist und dennoch nicht mal eine Sekunde dauert. Als Leistungssportler bereitet man sich immer und immer wieder auf diesen einen Moment vor. Wie unterscheidet sich dieser Moment in verschiedenen Sportarten? Gibt es ihn überhaupt in jeder Sportart?
Das Projekt „Do or Die“ fokussiert sich auf entscheidende und wichtige Situationen in unterschiedlichen Sportarten und zeigt dabei die Facetten und Vielseitigkeit des Leistungssports auf. In einem besonderen Konzept wird der Fokus auf genau diese Momente gelegt und greift den Aspekt des Scheiterns und Erfolgs auf. Es wird untersucht, wie sichtbar diese Augenblicke nach außen hin sind oder inwiefern entscheidende Momente auch nur im Kopf stattfinden und durch Emotionen zu erkennen sind.
In einer Mischklasse, bestehend aus sehenden und nicht-sehenden Kindern, welche nicht schriftlich oder spielerisch miteinander kommunizieren können, gehen einige soziale Aspekte und Lernübungen verloren. Partnerarbeiten und das gegenseitige Kontrollieren der Richtigkeit, beispielsweise bei der Anwendung von Satzzeichen, sind Möglichkeiten, welche die Kinder ohne ein gemeinsames Material nicht wahrnehmen können. Diese Arbeit ermöglicht ein gemeinsames Arbeiten aller Kinder durch dasselbe Material. Hierfür dienen dreidimensionale Objekte, welche im STL-Dateiformat zur Verfügung stehen. Es eignet sich für schriftliche und geografische Arbeiten. Des Weiteren ist ein Memory-Spiel enthalten, welches ebenso von sehenden und nicht-sehenden Kinder gespielt werden kann. Diese STLs können weltweit verschickt werden, sodass diese beliebig mit einem 3D-Drucker gedruckt werden können.
Die »tape foundry« ist eine interdisziplinäre Distributionsplattform für studentische Schriften, die Studierende auf dem großen Type-Design Markt neu platziert und einen Raum zur Entfaltung gibt. Besonders durch Instagram ist die heutige Type-Designszene größer denn je und viele Entwürfe gehen in der Maße unter. Um diesem Phänomen entgegenzuwirken wurde die »tape foundry« ins Leben gerufen. Sie versucht mit der Kombination aus Fotografie, Type Design und der Funktion als Kassettenlabel neue interdisziplinäre Wege zu gehen, um sich von der klassischen Ästhetik abzusetzen. Die Webseite stellt sich bewusst gegen gängige UX/UI Standards und setzt auf neue Nutzungsprinzipien kombiniert mit einer lauten kontrastreichen Bildwelt.
Die heutige, vielfältige kinetische Typografie hat eine lange Entwicklung durchgemacht. Die Darstellung dieser in einer zeitlichen Reihenfolge vermittelt ein Verständnis über Ursprung und Evolution. Die Publikation stellt die historische, analoge sowie die moderne, digitale Entwicklung dar. Dabei wird die Verbindung und der Einfluss der damaligen Gestaltung in der heutigen Umsetzung beleuchtet.
Die Plakatreihe erklärt drei Anwendungsmöglichkeiten der kinetischen Typografie. Hierbei werden teils reale Objekte nachgestellt, um die Wiedererkennung dieser im Alltag zu fördern. Gemeinsam zeigen die Plakate und die Publikation ein breites Spektrum der kinetischen Typografie und fördern das Verständnis dieser digitalen Umsetzung von Schrift in bewegter Form.