Light-addressable potentiometric sensor as a sensing element in plug-based microfluidic devices
- A plug-based microfluidic system based on the principle of the light-addressable potentiometric sensor (LAPS) is proposed. The LAPS is a semiconductor-based chemical sensor, which has a free addressability of the measurement point on the sensing surface. By combining a microfluidic device and LAPS, ion sensing can be performed anywhere inside the microfluidic channel. In this study, the sample solution to be measured was introduced into the channel in a form of a plug with a volume in the range of microliters. Taking advantage of the light-addressability, the position of the plug could be monitored and pneumatically controlled. With the developed system, the pH value of a plug with a volume down to 400 nL could be measured. As an example of plug-based operation, two plugs were merged in the channel, and the pH change was detected by differential measurement.
Verfasserangaben: | Ko-Ichiro Miyamoto, Takuya Sato, Minami Abe, Torsten WagnerORCiD, Michael Josef SchöningORCiD, Tatsuo Yoshinobu |
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DOI: | https://doi.org/10.3390/mi7070111 |
ISSN: | 2072-666X |
Titel des übergeordneten Werkes (Englisch): | Micromachines |
Verlag: | MDPI |
Verlagsort: | Basel |
Dokumentart: | Wissenschaftlicher Artikel |
Sprache: | Englisch |
Erscheinungsjahr: | 2016 |
Datum der Publikation (Server): | 06.07.2016 |
Freies Schlagwort / Tag: | chemical sensor; light-addressable potentiometric sensor; plug-based microfluidic device |
Jahrgang: | 7 |
Ausgabe / Heft: | 7 |
Erste Seite: | 111 |
Bemerkung: | This article belongs to the Special Issue "Micro/Nano Devices for Chemical Analysis" |
Link: | https://doi.org/10.3390/mi7070111 |
Zugriffsart: | weltweit |
Fachbereiche und Einrichtungen: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
FH Aachen / INB - Institut für Nano- und Biotechnologien | |
open_access (DINI-Set): | open_access |
collections: | Verlag / MDPI |
Open Access / Gold | |
Lizenz (Deutsch): | Creative Commons - Namensnennung |