Multiplexing system for automated characterization of a capacitive field-effect sensor array
- In comparison to single-analyte devices, multiplexed systems for a multianalyte detection offer a reduced assay time and sample volume, low cost, and high throughput. Herein, a multiplexing platform for an automated quasi-simultaneous characterization of multiple (up to 16) capacitive field-effect sensors by the capacitive–voltage (C–V) and the constant-capacitance (ConCap) mode is presented. The sensors are mounted in a newly designed multicell arrangement with one common reference electrode and are electrically connected to the impedance analyzer via the base station. A Python script for the automated characterization of the sensors executes the user-defined measurement protocol. The developed multiplexing system is tested for pH measurements and the label-free detection of ligand-stabilized, charged gold nanoparticles.
Author: | Tobias KarschuckORCiD, Stefan Schmidt, Stefan AchtsnichtORCiD, Arshak PoghossianORCiD, Patrick Wagner, Michael Josef SchöningORCiD |
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DOI: | https://doi.org/10.1002/pssa.202300265 |
ISSN: | 1862-6300 (Print) |
ISSN: | 1862-6319 (Online) |
Parent Title (English): | Physica Status Solidi A |
Publisher: | Wiley-VCH |
Place of publication: | Weinheim |
Document Type: | Article |
Language: | English |
Year of Completion: | 2023 |
Tag: | Capacitive field-effect sensor; Gold nanoparticles; Label-free detection; Multicell; Multiplexing |
Volume: | 220 |
Issue: | 22 |
Length: | 7 Seiten |
Note: | Corresponding author: Michael Josef Schöning |
Link: | https://doi.org/10.1002/pssa.202300265 |
Zugriffsart: | weltweit |
Institutes: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
FH Aachen / INB - Institut für Nano- und Biotechnologien | |
open_access (DINI-Set): | open_access |
collections: | Verlag / Wiley-VCH |
Open Access / Hybrid | |
Geförderte OA-Publikationen / DEAL Wiley | |
Licence (German): | Creative Commons - Namensnennung-Nicht kommerziell |