Visualization of Defects on a Cultured Cell Layer by Utilizing Chemical Imaging Sensor
- The chemical imaging sensor is a field-effect sensor which is able to visualize both the distribution of ions (in LAPS mode) and the distribution of impedance (in SPIM mode) inthe sample. In this study, a novel wound-healing assay is proposed, in which the chemical imaging sensor operated in SPIM mode is applied to monitor the defect of a cell layer brought into proximity of the sensing surface.A reduced impedance inside the defect, which was artificially formed ina cell layer, was successfully visualized in a photocurrent image.
Author: | Ko-ichiro Miyamoto, Yu Bing, Torsten WagnerORCiD, Tatsuo Yoshinobu, Michael Josef SchöningORCiD |
---|---|
DOI: | https://doi.org/10.1016/j.proeng.2015.08.806 |
ISSN: | 1877-7058 |
Parent Title (English): | Procedia Engineering |
Publisher: | Elsevier |
Place of publication: | Amsterdam |
Document Type: | Article |
Language: | English |
Year of Completion: | 2015 |
Volume: | 120 |
First Page: | 936 |
Last Page: | 939 |
Note: | Part of special issue "Eurosensors 2015" |
Link: | https://doi.org/10.1016/j.proeng.2015.08.806 |
Zugriffsart: | weltweit |
Institutes: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
FH Aachen / INB - Institut für Nano- und Biotechnologien | |
open_access (DINI-Set): | open_access |
collections: | Verlag / Elsevier |
Licence (German): | ![]() |