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This study has been performed to design the combination of the new ClearPET TM (ClearPET is a trademark of the Crystal Clear Collaboration), a small animal Positron Emission Tomography (PET) system, with a microComputed Tomography (microCT) scanner. The properties of different microCT systems have been determined by simulations based on GEANT4. We demonstrate the influence of the detector material and the X-ray spectrum on the obtained contrast. Four different detector materials (selenium, cadmium zinc telluride, cesium iodide and gadolinium oxysulfide) and two X-ray spectra (a molybdenum and a tungsten source) have been considered. The spectra have also been modified by aluminum filters of varying thickness. The contrast between different tissue types (water, air, brain, bone and fat) has been simulated by using a suitable phantom. The results indicate the possibility to improve the image contrast in microCT by an optimized combination of the X-ray source and detector material.
This paper examines the positive and negative aspects of a range of interpretations of nearest-neighbours models. Measures-oriented and distributionoriented verification methods are applied to categorial, probabilistic and descriptive interpretations of nearest neighbours used operationally in avalanche forecasting in Scotland and Switzerland. The dependence of skill and accuracy measures on base rate is illustrated. The purpose of the forecast and the definition of events are important variables in determining the quality of the forecast. A discussion of the application of different interpretations in operational avalanche forecasting is presented.