Refine
Year of publication
- 2024 (2)
- 2022 (9)
- 2021 (5)
- 2020 (8)
- 2019 (13)
- 2018 (18)
- 2017 (10)
- 2016 (17)
- 2015 (11)
- 2014 (10)
- 2013 (7)
- 2012 (14)
- 2011 (3)
- 2010 (6)
- 2009 (2)
- 2008 (7)
- 2007 (6)
- 2006 (5)
- 2005 (4)
- 2004 (6)
- 2003 (8)
- 2002 (4)
- 2001 (4)
- 2000 (8)
- 1999 (4)
- 1998 (3)
- 1997 (5)
- 1996 (2)
- 1995 (1)
- 1993 (3)
- 1992 (1)
- 1991 (2)
- 1990 (1)
- 1989 (2)
- 1988 (2)
- 1987 (2)
- 1985 (2)
Document Type
- Article (129)
- Conference Proceeding (61)
- Part of a Book (12)
- Book (4)
- Lecture (3)
- Other (3)
- Report (2)
- Doctoral Thesis (1)
- Patent (1)
- Review (1)
Keywords
- Finite-Elemente-Methode (16)
- Einspielen <Werkstoff> (13)
- shakedown analysis (9)
- FEM (6)
- Limit analysis (6)
- Shakedown analysis (6)
- limit analysis (6)
- Einspielanalyse (4)
- Shakedown (4)
- Technische Mechanik (4)
- Traglast (4)
- Traglastanalyse (4)
- shakedown (4)
- ratchetting (3)
- Analytischer Zulaessigkeitsnachweis (2)
- Biocomposites (2)
- Bruchmechanik (2)
- Druckbeanspruchung (2)
- Druckbehälter (2)
- Druckbelastung (2)
Institute
- Fachbereich Medizintechnik und Technomathematik (217) (remove)
Three-dimensional (3D) full-field measurements provide a comprehensive and accurate validation of finite element (FE) models. For the validation, the result of the model and measurements are compared based on two respective point-sets and this requires the point-sets to be registered in one coordinate system. Point-set registration is a non-convex optimization problem that has widely been solved by the ordinary iterative closest point algorithm. However, this approach necessitates a good initialization without which it easily returns a local optimum, i.e. an erroneous registration. The globally optimal iterative closest point (Go-ICP) algorithm has overcome this drawback and forms the basis for the presented open-source tool that can be used for the validation of FE models using 3D full-field measurements. The capability of the tool is demonstrated using an application example from the field of biomechanics. Methodological problems that arise in real-world data and the respective implemented solution approaches are discussed.
A new in vitro tool to investigate cardiac contractility under physiological mechanical conditions
(2019)
Numerical methods for limit and shakedown analysis. Deterministic and probabilistic problems.
(2003)
Human induced pluripotent stem cells (hiPSCs) have shown to be promising in disease studies and drug screenings [1]. Cardiomyocytes derived from hiPSCs have been extensively investigated using patch-clamping and optical methods to compare their electromechanical behaviour relative to fully matured adult cells. Mathematical models can be used for translating findings on hiPSCCMs to adult cells [2] or to better understand the mechanisms of various ion channels when a drug is applied [3,4]. Paci et al. (2013) [3] developed the first model of hiPSC-CMs, which they later refined based on new data [3]. The model is based on iCells® (Fujifilm Cellular Dynamics, Inc. (FCDI), Madison WI, USA) but major differences among several cell lines and even within a single cell line have been found and motivate an approach for creating sample-specific models. We have developed an optimisation algorithm that parameterises the conductances (in S/F=Siemens/Farad) of the latest Paci et al. model (2018) [5] using current-voltage data obtained in individual patch-clamp experiments derived from an automated patch clamp system (Patchliner, Nanion Technologies GmbH, Munich).
The discovery of human induced pluripotent stem cells reprogrammed from somatic cells [1] and their ability to differentiate into cardiomyocytes (hiPSC-CMs) has provided a robust platform for drug screening [2]. Drug screenings are essential in the development of new components, particularly for evaluating the potential of drugs to induce life-threatening pro-arrhythmias. Between 1988 and 2009, 14 drugs have been removed from the market for this reason [3]. The microelectrode array (MEA) technique is a robust tool for drug screening as it detects the field potentials (FPs) for the entire cell culture. Furthermore, the propagation of the field potential can be examined on an electrode basis. To analyze MEA measurements in detail, we have developed an open-source tool.
Kyphoplasty of Osteoporotic Fractured Vertebrae: A Finite Element Analysis about Two Types of Cement
(2019)
System und Verfahren zur Durchführung von Messungen biaxialer und kreuzförmiger Zugversuche, wobei ein Weg oder eine Kraft auf eine Materialprobe über mindestens zwei Nadelarme mit Nadeln geleitet wird, die in einem Gehäuse gelagert sind, wobei die Arme und/oder Nadelarme für eine ungehinderte Querkontraktion bei gleichmäßiger Lasteinleitung um eine Achse drehbar gelagert und seitlich auslenkbar sind.
We propose the so-called chance constrained programming model of stochastic programming theory to analyze limit and shakedown loads of structures under random strength with a lognormal distribution. A dual chance constrained programming algorithm is developed to calculate simultaneously both the upper and lower bounds of the plastic collapse limit and the shakedown limit. The edge-based smoothed finite element method (ES-FEM) is used with three-node linear triangular elements.
Rezension zu: K. Zimmermann, Technische Mechanik – multimedial. Fachbuch Verlag Leipzig (2000)
(2002)
Postural and metabolic benefits of using a forearm support walker in older adults with impairments
(2019)
Zusammenfassung: In der Orthopädie zählt der therapeutische Ultraschall als Mittel zur Prävention und Therapiebegleitung. Er hat mechanische, thermische und physiko-chemische Auswirkungen auf den menschlichen Körper. Um mehr Erkenntnisse über die thermischen Auswirkungen zu erlangen, wurden Versuche an einem Hydrogel-Phantom und an Probanden durchgeführt. Dabei entstand eine signifikante Erwärmung des Gewebes, welche beim Probandenversuch an der Oberfläche und beim Hydrogelversuch in der Tiefe gemessen wurde.
Summary: In orthopaedics, therapeutic ultrasound is a tool of prevention and therapy support. It has mechanical, thermal and physico-chemical effects on the human body. Tests with a hydrogel phantom and with human probands have been performed in order to obtain more knowledge about their thermal effects. Both tests measured temperature increases in cell tissue, on the surface with the human proband test and in depth with the hydrogel phantom test.
Prosthetic textile implants of different shapes, sizes and polymers are used to correct the apical prolapse after hysterectomy (removal of the uterus). The selection of the implant before or during minimally invasive surgery depends on the patient’s anatomical defect, intended function after reconstruction and most importantly the surgeon’s preference. Weakness or damage of the supporting tissues during childbirth, menopause or previous pelvic surgeries may put females in higher risk of prolapse. Numerical simulations of reconstructed pelvic floor with weakened tissues and organ supported by textile product models: DynaMesh®-PRS soft, DynaMesh®-PRP soft and DynaMesh®-CESA from FEG Textiletechnik mbH, Germany are compared.