Refine
Year of publication
Document Type
- Article (1578)
- Conference Proceeding (239)
- Book (96)
- Part of a Book (59)
- Doctoral Thesis (27)
- Patent (17)
- Report (15)
- Other (8)
- Habilitation (4)
- Lecture (3)
- Preprint (3)
- Course Material (1)
- Review (1)
- Talk (1)
Keywords
- Biosensor (25)
- Finite-Elemente-Methode (16)
- CAD (15)
- civil engineering (14)
- Bauingenieurwesen (13)
- Einspielen <Werkstoff> (13)
- shakedown analysis (9)
- FEM (6)
- Limit analysis (6)
- Shakedown analysis (6)
- limit analysis (6)
- Clusterion (5)
- Air purification (4)
- Einspielanalyse (4)
- Hämoglobin (4)
- LAPS (4)
- Lipopolysaccharide (4)
- Luftreiniger (4)
- Natural language processing (4)
- Plasmacluster ion technology (4)
- Raumluft (4)
- Shakedown (4)
- Technische Mechanik (4)
- Traglast (4)
- Traglastanalyse (4)
- hydrogen peroxide (4)
- shakedown (4)
- CellDrum (3)
- Field-effect sensor (3)
- Information extraction (3)
- Kohlenstofffaser (3)
- Label-free detection (3)
- Light-addressable potentiometric sensor (3)
- Paired sample (3)
- Sonde (3)
- biosensor (3)
- biosensors (3)
- impedance spectroscopy (3)
- lipopolysaccharides (3)
- ratchetting (3)
- Analytischer Zulaessigkeitsnachweis (2)
- Architektur (2)
- Bacillus atrophaeus (2)
- Biocomposites (2)
- Bruchmechanik (2)
- Capacitive field-effect sensor (2)
- Clustering (2)
- Druckbeanspruchung (2)
- Druckbehälter (2)
- Druckbelastung (2)
- Einspiel-Analyse (2)
- Eisschicht (2)
- Empirical process (2)
- Erythrozyt (2)
- Fehlerstellen (2)
- Fibroblast (2)
- Force (2)
- Goodness-of-fit test (2)
- Incomplete data (2)
- Independence test (2)
- Iterative learning control (2)
- Machine learning (2)
- Natural fibres (2)
- Parametric bootstrap (2)
- Pflanzenphysiologie (2)
- Pflanzenscanner (2)
- Polymer-matrix composites (2)
- Potentiometry (2)
- Raman spectroscopy (2)
- Ratcheting (2)
- Rohr (2)
- Rohrbruch (2)
- Stahl (2)
- Stickstoffmonoxid (2)
- Stiffness (2)
- Stress concentrations (2)
- Tobacco mosaic virus (TMV) (2)
- acetoin (2)
- architecture (2)
- biopotential electrodes (2)
- burst pressure (2)
- burst tests (2)
- capacitive field-effect sensors (2)
- carbonized rice husk (2)
- celldrum technology (2)
- constructive alignment (2)
- damage (2)
- examination (2)
- field-effect sensor (2)
- flaw (2)
- frequency mixing magnetic detection (2)
- gas sensor (2)
- likelihood ratio test (2)
- limit load (2)
- load limit (2)
- locomotion (2)
- long-term retention (2)
- multimodal (2)
- muscle fascicle behavior (2)
- nanostructured carbonized plant parts (2)
- nanostrukturierte carbonisierte Pflanzenteile (2)
- nitric oxide gas (2)
- not identically distributed (2)
- pipes (2)
- plant scanner (2)
- practical learning (2)
- sterilisation (2)
- surface modification (2)
- tension–torsion loading (2)
- tobacco mosaic virus (TMV) (2)
- ultrasound (2)
- ultrasound imaging (2)
- vessels (2)
- (Bio)degradation (1)
- 3-nitrofluoranthene (1)
- Acceleration (1)
- Achilles tendon (1)
- Active learning (1)
- Adaptive control (1)
- Adsorption (1)
- Afterload (1)
- Ageing (1)
- Agent-based simulation (1)
- AlterG (1)
- Alternating plasticity (1)
- Alzheimer's disease (1)
- Analysis (1)
- Anastomose (1)
- Anastomosis (1)
- Anastomotic leakage (1)
- Anatomy (1)
- Annulus Fibrosus (1)
- Architectural design (1)
- Architectural gear ratio (1)
- Arthosetherapie (1)
- Assistive technology (1)
- Asymptotic efficiency (1)
- Asymptotic relative efficiency (1)
- Aufschlagversuch (1)
- Autofluoreszenzverfahren (1)
- Autolysis (1)
- Automatic control (1)
- Axialbelastung (1)
- Axially cracked pipe (1)
- BTEX compounds (1)
- Bacillus atrophaeus spores (1)
- Bacillus sp (1)
- Bacterial cellulose (1)
- Bakterien (1)
- Balance (1)
- Basis Reduktion (1)
- Basis reduction (1)
- Bein (1)
- Bicharakteristikenverfahren (1)
- Bio-Sensors (1)
- Bioabsorbable (1)
- Biomechanical simulation (1)
- Biomechanics (1)
- Biomechanik (1)
- Biomedizinische Technik (1)
- Biomolecular logic gate (1)
- Biophoton (1)
- Bioreaktor (1)
- Biosensorik (1)
- Biosolubilization (1)
- Bladder (1)
- Blitzschutz (1)
- Blutzellenlagerung (1)
- Bone quality and biomechanics (1)
- Bone sawing (1)
- Booster Station (1)
- Bootstrap (1)
- Bootstrapping (1)
- Brennkraftmaschine (1)
- Brennstoffeinspritzsystem (1)
- Brownian Pillow (1)
- CAD ; (1)
- CNOT (1)
- CO (1)
- Calorimetric gas sensor (1)
- Capacitive field-effect (1)
- Capacitive model (1)
- Carbon sources (1)
- Cardiac myocytes (1)
- Cardiac tissue (1)
- Categorial variable (1)
- Cell permeability (1)
- Cellular force (1)
- Cellulose nanostructure (1)
- Cement infiltration (1)
- Cementoblast (1)
- Censored data (1)
- Chance constrained programming (1)
- Chemical images (1)
- Chemical imaging (1)
- Chemical imaging sensor (1)
- Chemical sensor (1)
- Choleratoxin B (1)
- Circular Dichroism (1)
- Cloud Computing (1)
- Cloud Service Broker (1)
- Co-managed care (1)
- Coat protein (1)
- Coefficient of ocular rigidity (1)
- Collective risk model (1)
- Competitiveness (1)
- Complex System (1)
- Complex-valued eigenvalues (1)
- Compliance (1)
- Compression (1)
- Computational biomechanics (1)
- Concomitant (1)
- Conducing polymer (1)
- Conductive Boundary Condition (1)
- Constitutive model (1)
- Contractile tension (1)
- Contractility (1)
- Convex optimization (1)
- Corneo-scleral shell (1)
- Cost-effectiveness (1)
- Coverage probability (1)
- Cramér-von-Mises statistic (1)
- Cramér-von-Mises test (1)
- Cross border adjustment mechanism (1)
- Crámer–von-Mises distance (1)
- Culture media (1)
- C–V method (1)
- DNA (1)
- DNA biosensor (1)
- DNA hybridization (1)
- DPA (dipicolinic acid) (1)
- Damage mechanics theory (1)
- Dattel (1)
- Decomposition (1)
- Deep Learning (1)
- Deep learning (1)
- Deformation (1)
- Dehydrogenase (1)
- Dekontamination (1)
- Design-by-analysis (1)
- Diaphorase (1)
- Differential tonometry (1)
- Disc Degeneration (1)
- Discontinuous fractures (1)
- Discrete Optimization (1)
- Distorsion des oberen Sprunggelenks (1)
- Druckgeräte (1)
- Drug simulation (1)
- Dry surfaces (1)
- E-Mobility (1)
- ECT (1)
- EEG (1)
- EIS capacitive sensor (1)
- ELISA (1)
- EPN (1)
- ES-FEM (1)
- Effizienz (1)
- Eigenvalue trajectories (1)
- Einspiel-Kriterium (1)
- Einspielen (1)
- Elastizität (1)
- Elastodynamik (1)
- Elastostatics (1)
- Elderly (1)
- Electrolyte–insulator–semiconductor (1)
- Electromagnetism (1)
- Electromechanical modeling (1)
- Elektrodynamik (1)
- Elektroenzephalographie (1)
- Elektromyographie (1)
- Elektrostimulation (1)
- Elemental (1)
- End-to-end colorectal anastomosis (1)
- Endothelial cells (1)
- Endothelial dysfunction (1)
- Endothelzelle (1)
- Energy market design (1)
- Energy-intensive industry (1)
- Enterprise information systems (1)
- Environmental impact (1)
- Enzymatic biosensor (1)
- Enzyme biosensor (1)
- Enzyme coverage (1)
- Enzyme logic gate (1)
- Enzyme nanocarrier (1)
- Enzyme-linked immunosorbent assay (1)
- Epithel (1)
- Equivalence test (1)
- Esophageal Doppler monitor (1)
- Evolution of damage (1)
- Exact Ilyushin yield surface (1)
- Experiment (1)
- Extension fracture (1)
- Extension strain criterion (1)
- Extensor (1)
- External knee adduction moments (1)
- Eyeball (1)
- FEM-Programm (1)
- FEM-computation (1)
- FGF23 (1)
- FS-FEM (1)
- Fall prevention (1)
- Fault approximation (1)
- Fault detection (1)
- Festkörper (1)
- Field effect (1)
- Field-effect biosensor (1)
- Field-effect device (1)
- Finite element analysis (1)
- Finite element analysis (FEA) (1)
- Finite element method (1)
- Finite element modelling (1)
- First Order Reliabiblity Method (1)
- First-order reliability method (1)
- Fließgrenze (1)
- Floor prices (1)
- Fluorescence (1)
- Forces (1)
- Fracture configuration (1)
- Fracture simulation (1)
- Freeze–thaw process (1)
- Frequency adaption (1)
- Frequency mixing magnetic detection (1)
- Functional Delta Method (1)
- Fußball (1)
- GaAs hot electron injector (1)
- Gamma distribution (1)
- Gas sensor (1)
- Geriatric (1)
- German (1)
- Glaucoma (1)
- Global and local collapse (1)
- Glucose biosensor (1)
- Glucose oxidase (1)
- Gold nanoparticle (1)
- Gold nanoparticles (1)
- Gonarthrose (1)
- Goodness-of-fit tests for uniformity (1)
- Grenzwertberechnung (1)
- Grid Computing (1)
- Ground-level falls (1)
- Growth modelling (1)
- Gunn diode (1)
- Hadamard differentiability (1)
- Haemodialysis (1)
- Handbike (1)
- Harnleiter (1)
- Heart tissue culture (1)
- Heavy metal detection (1)
- Hemoglobin structure (1)
- Heterostructure (1)
- High throughput experimentation (1)
- Hip fractures (1)
- Hodgkin–Huxley models (1)
- Hoeffding-Blum-Kiefer-Rosenblatt independence test (1)
- Homogenization (1)
- Hotelling’s T² test (1)
- Hotplate (1)
- Human Factors (1)
- Human-Computer interaction (1)
- Hydrodynamik (1)
- Hydrogel (1)
- Hydrogen peroxide (1)
- Hydrogen sensor (1)
- Hypothesentests (1)
- Hämoglobinstruktur (1)
- I3S 2005 (1)
- ISFET (1)
- Image Reconstruction (1)
- Impedance Spectroscopy (1)
- Impedance spectroscopy (1)
- Induced pluripotent stem cells (1)
- Information Extraction (1)
- Information Integration Tools (1)
- Inotropic compounds (1)
- Integrated empirical distribution (survival) function (1)
- Interior transmission problem (1)
- International Symposium on Sensor Science (1)
- Intervertebral Disc (1)
- Intradiscal Pressure (1)
- Inverse Scattering (1)
- Inverse dynamic problem (1)
- Inverse kinematic problem (1)
- Inverse scattering problem (1)
- Ion channels (1)
- Kinematics (1)
- Kinetic energy (1)
- Kinetics (1)
- Klotho (1)
- Knee (1)
- Kniegelenkarthrose (1)
- Knochen (1)
- Knochenbildung (1)
- Knochenchirugie (1)
- Knochendichte (1)
- Knowledge Management (1)
- Krypton (1)
- Krypton-85 (1)
- Körpertemperatur (1)
- LED chip (1)
- LISA (1)
- LPS (1)
- Lab-on-Chip (1)
- Langevin theory (1)
- Layer-by-layer adsorption (1)
- LbL films (1)
- Level sensor (1)
- Lichtstreuungsbasierte Instrumente (1)
- Light-addressable Potentiometric Sensor (1)
- Liver (1)
- Load modeling (1)
- Long COVID (1)
- MBST (1)
- MCDA (1)
- MEMS (1)
- MOS (1)
- Magnetic nanoparticles (1)
- Main sensitivity (1)
- Manipulated variables (1)
- Marginal homogeneity (1)
- Marginal homogeneity test (1)
- Market modeling (1)
- Materialermüdung (1)
- Mechanical simulation (1)
- Mechanics (1)
- Mechanische Beanspruchung (1)
- Mechanotransduction (1)
- Medusomyces gisevi (1)
- Metascintillator (1)
- Microbial adhesion (1)
- Microcirculation (1)
- Micromagnetic simulation (1)
- Microreactors (1)
- Mild cognitive impairment (1)
- Mobility (1)
- Mobility tests (1)
- Mobility transition (1)
- Model-driven software engineering (1)
- Mohr–Coulomb criterion (1)
- Multi-criteria decision analysis (1)
- Multi-dimensional wave propagation (1)
- Multi-sample problem (1)
- Multianalyte detection (1)
- Multicell (1)
- Multimode failure (1)
- Multiple TOF kernels (1)
- Multiplexing (1)
- Muscle (1)
- Muscle Fascicle (1)
- Muscle Force (1)
- Muscle fibers (1)
- Musculoskeletal model (1)
- Musculoskeletal system (1)
- Myocardial infarction and cardiac death (1)
- NONOate (1)
- Nano Materials (1)
- Nanomaterial (1)
- Nanoparticles (1)
- Nanopartikel (1)
- Nanostructuring (1)
- Nanotechnologie (1)
- Nanotechnology ; Microelectronics ; Biosensors ; Superconductor ; MEMS (1)
- Natriumhypochlorit (1)
- Natural Language Processing (1)
- Natural language understanding (1)
- Negative impedance convertor (1)
- Neural Network (1)
- Neuromuskuläres System (1)
- Niacin (1)
- Nichtlineare Gleichung (1)
- Nichtlineare Optimierung (1)
- Nichtlineare Welle (1)
- Nitric Oxide (1)
- Nitric Oxide Donor (1)
- Non-linear optimization (1)
- Non-parallel fissures (1)
- Nonequilibrium dynamics (1)
- Nonlinear Dynamics (1)
- Nucleus Pulposus (1)
- Numerical inversion of Laplace transforms (1)
- Numerical linear algebra (1)
- O2 plasma (1)
- Ocular blood flow (1)
- Ontologie <Wissensverarbeitung> (1)
- Ontology Engineering (1)
- Organic light-emitting diode display (1)
- Organkultur (1)
- Organophosphorus (1)
- Ostazine Orange (1)
- Osteoporose (1)
- Osteoporosis (1)
- PFM (1)
- PTH (1)
- Paralympic sport (1)
- Passive stretching (1)
- Pelvic floor dysfunction (1)
- Pelvic muscle (1)
- Penicillin (1)
- Permeability (1)
- Permeabilität (1)
- Peroxidase (1)
- Pflanzenstress (1)
- Pharmacology (1)
- Phenylalanine determination (1)
- Phosphate (1)
- Physiology (1)
- Plant virus (1)
- Plastizität (1)
- Poly(allylamine hydrochloride) (1)
- Poly(d,l-lacticacid) (1)
- Polyimide (1)
- Polylactide acid (1)
- Post-COVID-19 syndrome (1)
- Preference assessment (1)
- Pressure loaded crack-face (1)
- Pressure-volume relationship (1)
- Prevention (1)
- Process model (1)
- Product-integration (1)
- Profile Extraction (1)
- Profile extraction (1)
- Progressive plastic deformation (1)
- Prophylaxis (1)
- Proteine (1)
- Proximal humerus fracture (1)
- Pseudomonas putida (1)
- Psychiatrische Biomarker (1)
- Pulsations (1)
- Pump System (1)
- Quartz crystal nanobalance (QCN) (1)
- Quartz micro balances (1)
- Query learning (1)
- RVA (1)
- Random variable (1)
- Ratchetting (1)
- Raumfahrt (1)
- Reaction-diffusion (1)
- Real-time monitoring (1)
- Recombinant activated protein C (1)
- Reconstruction (1)
- Red blood cell storage (1)
- Regionalization (1)
- Rehabilitation Technology and Prosthetics (1)
- Rehabilitation engineering (1)
- Rehabilitationsmedizin (1)
- Rehabilitatives Training (1)
- Relation classification (1)
- Reliability analysis (1)
- Reliability of structures (1)
- Reproducible research (1)
- Resampling test (1)
- Resistive temperature detector (1)
- Resolvent Operator (1)
- Resonance-mode measurement (1)
- Retinal vessel analysis (1)
- Retinal vessels (1)
- Riboflavin (1)
- Robotic rehabilitation (1)
- Robotik (1)
- Rotator cuff (1)
- Running (1)
- S-FEM (1)
- Sampling methods (1)
- ScaLAPACK (1)
- Schienbeinschoner (1)
- Schlafspindeldetektion (1)
- Schwammknochen (1)
- Semi-parametric random censorship model (1)
- Sensitivity (1)
- Sepsis (1)
- Septic cardiomyopathy (1)
- Shakedown criterion (1)
- Silk fibroin (1)
- Simulation (1)
- Simultaneous determination (1)
- Skeletal muscle (1)
- Sleep EEG (1)
- Small Aral Sea (1)
- Sn₃O₄ (1)
- Software and systems modeling (1)
- Solid amalgam electrodes (1)
- Spleen (1)
- Sprunggelenkorthesen (1)
- Statics (1)
- Steel industry (1)
- Sterilisation process (1)
- Stochastic programming (1)
- Strukturanalyse (1)
- SunRav BookEditor (1)
- Supraleiter (1)
- Surface microorganisms (1)
- Surgical Navigation and Robotics (1)
- Surgical staplers (1)
- Survival analysis (1)
- Swabbing (1)
- TMV adsorption (1)
- TOF PET (1)
- Ta₂O₅ gate (1)
- Technical Operations Research (TOR) (1)
- Temperaturabhängigkeit (1)
- Tendon Rupture (1)
- Tendon properties (1)
- Tendons (1)
- Tension (1)
- Text Mining (1)
- Text mining (1)
- Thiamine (1)
- Tin oxide (1)
- Tinetti test (1)
- Tissue Engineering (1)
- Tobacco mosaic virus (1)
- Torsion (1)
- Torsionsbelastung (1)
- Tragfähigkeit (1)
- Training (1)
- Trainingsgerät (1)
- Transmission Eigenvalues (1)
- Trinkwassersicherheit (1)
- Trustworthy artificial intelligence (1)
- UML (1)
- Ultrasound (1)
- Uniaxial compression test (1)
- Unified Modeling Language (1)
- Ureter (1)
- Vapnik–Čhervonenkis class (1)
- Variable height stapler design (1)
- Vascular response (1)
- Vasomotions (1)
- Velocity (1)
- Vergleich von Experimenten (1)
- Vertebroplastie (1)
- Vertebroplasty (1)
- Viscous flow (1)
- Viskose Strömung (1)
- Viskosität (1)
- Visual field asymmetry (1)
- Vitamin A (1)
- Vitamin B (1)
- Vitamin D (1)
- Volterra integral equation (1)
- Volume of confidence regions (1)
- Volume status (1)
- Volumes of confidence regions (1)
- Wafer (1)
- Wasserbrücke (1)
- Wasserstoffperoxid (1)
- Wellen (1)
- Wolff's Law (1)
- Wolffsches Gesetz (1)
- Workflow (1)
- Workflow Orchestration (1)
- Wundheilung (1)
- XOR (1)
- Xenon (1)
- Zeta potential (1)
- Zug-Druck Belastung (1)
- Zug-Druck-Beanspruchung (1)
- Zug-Druck-Belastung (1)
- acetoin reductase (1)
- achilles tendon (1)
- actin cytoskeleton (1)
- activated nanostructured carbon (1)
- adipose-derived stromal cells (ASCs) (1)
- adsorption (1)
- agility (1)
- aktivierte nanostrukturierte Kohlenstofffaser (1)
- alcoholic beverages (1)
- allocation (1)
- alternierend Verformbarkeit (1)
- ammonia gas sensors (1)
- amperometric biosensors (1)
- amperometric sensor (1)
- anaesthetic complications (1)
- anisotropy (1)
- ankle braces (1)
- ankle sprain (1)
- annealing (1)
- antimony doped tin oxide (1)
- aortic perfusion (1)
- aromatic amines (1)
- arthrosis therapy (1)
- artificial olfactory image (1)
- asymptotic relative efficiency (1)
- atomic layer deposition (1)
- autofluorescence-based detection system (1)
- barium strontium titanate (1)
- biaxial tensile experiment (1)
- bicharacteristics (1)
- bioburdens (1)
- biocompatible (1)
- biocompatible materials (1)
- biodegradabl (1)
- biodegradable electronic devices (1)
- biomechanics (1)
- bone density (1)
- bone structure (1)
- bootstrap (1)
- calorimetric gas sensor (1)
- calorimetric gas sensor;hydrogen peroxide;wireless sensor system (1)
- cancellous bone (1)
- capacitive electrolyte–insulator–semiconductor sensors (1)
- capacitive field-effect biosensor (1)
- capacitive field-effect sensor (1)
- capillary micro-droplet cell (1)
- carbon electrodes (1)
- carcinogens (1)
- cardiomyocyte biomechanics (1)
- catalytic decomposition (1)
- catalytic metal (1)
- cell aerosolization (1)
- cell atomization (1)
- central symmetry test (1)
- cerebral small vessel disease (1)
- chance constrained programming (1)
- chemical reduction method (1)
- chemical sensor (1)
- cholera toxin B (1)
- cognitive impairment (1)
- community dwelling (1)
- complete block symmetry (1)
- computational fluid dynamics analysis (1)
- conditional excess distribution (1)
- conditional expectation principle (1)
- confidence interval (1)
- connective tissue (1)
- constitutive modeling (1)
- contactless conductivity sensor (1)
- contractile tension (1)
- correlation (1)
- coupled Néel–Brownian relaxation dynamics (1)
- covariance principle (1)
- cross sensitivity (1)
- cytosolic water diffusion (1)
- date palm tree (1)
- dental trauma (1)
- design-by-analysis (1)
- dialysis (1)
- difficult airway (1)
- direct method (1)
- distance learning (1)
- distorted element (1)
- doped metal oxide (1)
- doped silicon (1)
- doping (1)
- double-lumen tube intubation (1)
- drinking water safety (1)
- drop jump (1)
- e-books (1)
- e-issues (1)
- ecological structure (1)
- efficiency (1)
- eigensolvers (1)
- elastic solids (1)
- electrical capacitance tomography (1)
- electro-migration (1)
- electrolyte-insulator semiconductor sensor (EIS) (1)
- electromyography (1)
- electronic nose (1)
- electronic noses dendronized polymers inverted mesa technology (1)
- encapsulation materials (1)
- endoluminal (1)
- endospores (1)
- energy absorption (1)
- energy dissipation (1)
- enzymatic (bio)degradation (1)
- enzymatic biosensor (1)
- enzymatic methods (1)
- enzyme cascade (1)
- enzyme immobilisation (1)
- enzyme immobilization (1)
- epithelization (1)
- exchangeability test (1)
- extracorporeal membrane oxygenation (1)
- fatigue analyses (1)
- fenitrothion (1)
- fibroin (1)
- fibulare Bandruptur (1)
- field-effect structure (1)
- finite element analysis (1)
- fluidic (1)
- force generation (1)
- forecast (1)
- forehead EEG (1)
- fortschreitende plastische Deformation (1)
- frequency mixing (1)
- functional data (1)
- gait (1)
- gas sensor array (1)
- glucose (1)
- glucose oxidase (GOx) (1)
- gonarthrosis (1)
- goodness-of-fit test (1)
- graphene oxide (1)
- healthy aging (1)
- heater metallisation (1)
- heavy metals (1)
- hemoglobin (1)
- hemoglobin dynamics (1)
- hiPS cardiomyocytes (1)
- high-intensity exercise (1)
- high-k material (1)
- high-temperature stability (1)
- horseradish peroxidase (HRP) (1)
- huge dimensional data (1)
- human dermal fibroblasts (1)
- humic acid (1)
- humidity (1)
- hydrogel (1)
- hydroxylation (1)
- hyper-gravity (1)
- hyperelastic (1)
- hypo-gravity (1)
- image sensor (1)
- imaging (1)
- immobilization (1)
- in-ear EEG (1)
- in-situ monitoring (1)
- independence test (1)
- intraclass correlation coefficient (1)
- ion-selective electrodes (1)
- key performance indicators (1)
- kontraktile Spannung (1)
- konvexe Optimierung (1)
- krypton xenon hydrate (1)
- lab-on-a-chip (1)
- lab-on-chip (1)
- lable-free detection (1)
- large language models (1)
- layer expansion (1)
- layer-by-layer technique (1)
- lenslet array (1)
- light scattering analysis (1)
- light-addressable potentiometric sensor (1)
- light-addressing technologies (1)
- lightning flash (1)
- lignite (1)
- limit and shakedown analysis (1)
- linear kinematic hardening (1)
- lipopolysaccharide (1)
- load carrying capacity (1)
- lower bound theorem (1)
- magnetic actuation (1)
- magnetic beads (1)
- magnetic biosensing (1)
- magnetic frequency mixing technique (1)
- magnetic nanoparticles (1)
- magnetic particles (1)
- magnetic relaxation (1)
- magnetic sandwich immunoassay (1)
- magnetic sensing (1)
- magnetic separation (1)
- magnetic tweezers (1)
- magnetophoretic velocity (1)
- material shakedown (1)
- matrix method (1)
- mechanical buffer (1)
- mechanical waves (1)
- metagenomics (1)
- metal oxide (1)
- metal-oxide-semiconductor structure (1)
- microbial diversity (1)
- micromagnetic simulation (1)
- microreactor (1)
- microwave generation (1)
- modeling biosensor (1)
- modelling (1)
- modified electrode (1)
- multi-functional material (1)
- multi-interface measurement (1)
- multinomial distribution (1)
- multiparametric immunoassays (1)
- multivariate normal distribution (1)
- muscle mechanics (1)
- nanobelts (1)
- nanomaterials (1)
- naphtols (1)
- nitrogen oxides (1)
- non-simplex S-FEM elements (1)
- nonlinear kinematic hardening (1)
- nonlinear optimization (1)
- nonlinear solids (1)
- nonlinear tensor constitutive equation (1)
- novel photoexcitation method (1)
- optical sensor setup (1)
- optical spore trapping (1)
- optical trapping (1)
- organic PVC membranes (1)
- organosilanes (1)
- overload (1)
- pH sensors (1)
- pH-based biosensing (1)
- parabolic flight (1)
- pattern-size reduction (1)
- penicillin (1)
- penicillinase (1)
- performance analysis (1)
- performance testing (1)
- phenols (1)
- photoelectrochemistry (1)
- physiology (1)
- plant stress (1)
- plant virus detection (1)
- plasma generated ions (1)
- plastic deformation (1)
- plug-based microfluidic device (1)
- poly(d, l-lactic acid) (1)
- polyaniline (1)
- polymer composites (1)
- porous Pt electrode (1)
- portfolio risk (1)
- prevention (1)
- principal component (1)
- probabilistic fracture mechanics (1)
- protein (1)
- psychosocial (1)
- quantum charging (1)
- random effects (1)
- random effects meta-regression model (1)
- rehabilitation (1)
- reliability (1)
- reliability analysis (1)
- reliability of structures (1)
- retinal microvasculature (1)
- retinal vessels (1)
- rhAPC (1)
- running (1)
- rupture of the fibular ligament (1)
- sEMG (1)
- sarcomere operating length (1)
- scanned light pulse technique (1)
- screen-printing (1)
- second-order reliability method (1)
- self-aligned patterning (1)
- semantic role labeling (1)
- sensing properties (1)
- sensors (1)
- separable Hilbert space (1)
- series elastic element behavior (1)
- shakedown analyses (1)
- shotgun sequencing (1)
- shoulder (1)
- silanization (1)
- simulation (1)
- smooth muscle contraction (1)
- softs (1)
- spatial resolution (1)
- speaker attribution (1)
- sprint start (1)
- standard error of measurement (1)
- sterility tests (1)
- sterilization (1)
- sterilization conditions (1)
- sterilization efficacy (1)
- sterilization methods (1)
- stiffness (1)
- stochastic programming (1)
- strain energy function (1)
- stretch reflex (1)
- stretch-shortening cycle (1)
- subsurface ice research (1)
- subsurface probe (1)
- superparamagnetic bead (1)
- superparamagnetic nanoparticles (1)
- surface functionalization (1)
- survival (1)
- swift heavy ions (1)
- temperature (1)
- tendon rupture (1)
- test-retest reliability (1)
- testing hypotheses (1)
- thermal ratcheting (1)
- thick-film technology (1)
- thin-film microsensors (1)
- tilted constant illumination (1)
- titanium dioxide photoanode (1)
- training simulator (1)
- tri-lineage differentiation (1)
- turnip vein clearing virus (TVCV) (1)
- twin-fluid atomizer (1)
- ultrasonography (1)
- ultrathin gate insulators (1)
- uniformly most powerful invariant test (1)
- unloading (1)
- validation methods (1)
- videolaryngoscopy (1)
- virgin passive (1)
- virtual reality (1)
- viscoelasticity (1)
- visualization (1)
- voltammetry (1)
- wafer-level testing (1)
- walking (1)
- walking gait (1)
- water bridge phenomenon (1)
- wound healing (1)
- yield stress (1)
- · Psychiatrische Erkrankungen/Diagnostik (1)
Institute
- Fachbereich Medizintechnik und Technomathematik (2052) (remove)
This paper develops a new finite element method (FEM)-based upper bound algorithm for limit and shakedown analysis of hardening structures by a direct plasticity method. The hardening model is a simple two-surface model of plasticity with a fixed bounding surface. The initial yield surface can translate inside the bounding surface, and it is bounded by one of the two equivalent conditions: (1) it always stays inside the bounding surface or (2) its centre cannot move outside the back-stress surface. The algorithm gives an effective tool to analyze the problems with a very high number of degree of freedom. Our numerical results are very close to the analytical solutions and numerical solutions in literature.
Image reconstruction analysis for positron emission tomography with heterostructured scintillators
(2022)
The concept of structure engineering has been proposed for exploring the next generation of radiation detectors with improved performance. A TOF-PET geometry with heterostructured scintillators with a pixel size of 3.0×3.1×15 mm3 was simulated using Monte Carlo. The heterostructures consisted of alternating layers of BGO as a dense material with high stopping power and plastic (EJ232) as a fast light emitter. The detector time resolution was calculated as a function of the deposited and shared energy in both materials on an event-by-event basis. While sensitivity was reduced to 32% for 100 μm thick plastic layers and 52% for 50 μm, the CTR distribution improved to 204±49 ps and 220±41 ps respectively, compared to 276 ps that we considered for bulk BGO. The complex distribution of timing resolutions was accounted for in the reconstruction. We divided the events into three groups based on their CTR and modeled them with different Gaussian TOF kernels. On a NEMA IQ phantom, the heterostructures had better contrast recovery in early iterations. On the other hand, BGO achieved a better contrast to noise ratio (CNR) after the 15th iteration due to the higher sensitivity. The developed simulation and reconstruction methods constitute new tools for evaluating different detector designs with complex time responses.
This paper investigates the interior transmission problem for homogeneous media via eigenvalue trajectories parameterized by the magnitude of the refractive index. In the case that the scatterer is the unit disk, we prove that there is a one-to-one correspondence between complex-valued interior transmission eigenvalue trajectories and Dirichlet eigenvalues of the Laplacian which turn out to be exactly the trajectorial limit points as the refractive index tends to infinity. For general simply-connected scatterers in two or three dimensions, a corresponding relation is still open, but further theoretical results and numerical studies indicate a similar connection.
In this paper, methods of sample preparation for potentiometric measurement of phenylalanine are presented. Basing on the spectrophotometric measurements of phenylalanine, the concentrations of reagents of the enzymatic reaction (10 mM L-Phe, 0,4 mM NAD+, 2U L-PheDH) were determined. Then, the absorption spectrum of the reaction product, NADH, was monitored (maximum peak at 340 nm). The results obtained by the spectrophotometric method were compared with the results obtained by the colourimetry, using pH indicators. The above-mentioned two methods will be used as references for potentiometric measurements of phenylalanine concentration.
In this paper, methods of surface modification of different supports, i.e. glass and polymeric beads for enzyme immobilisation are described. The developed method of enzyme immobilisation is based on Schiff’s base formation between the amino groups on the enzyme surface and the aldehyde groups on the chemically modified surface of the supports. The surface of silicon modified by APTS and GOPS with immobilised enzyme was characterised by atomic force microscopy (AFM), time-of-flight secondary ion mass spectroscopy (ToF-SIMS) and infrared spectroscopy (FTIR). The supports with immobilised enzyme (urease) were also tested in combination with microreactors fabricated in silicon and Perspex, operating in a flow-through system. For microreactors filled with urease immobilised on glass beads (Sigma) and on polymeric beads (PAN), a very high and stable signal (pH change) was obtained. The developed method of urease immobilisation can be stated to be very effective.
An enzyme-based multi-parameter biosensor is developed for monitoring the concentration of formate, d-lactate, and l-lactate in biological samples. The sensor is based on the specific dehydrogenation by an oxidized β-nicotinamide adenine dinucleotide (NAD+)-dependent dehydrogenase (formate dehydrogenase, d-lactic dehydrogenase, and l-lactic dehydrogenase, respectively) in combination with a diaphorase from Clostridium kluyveri (EC 1.8.1.4). The enzymes are immobilized on a platinum working electrode by cross-linking with glutaraldehyde (GA). The principle of the determination scheme in case of l-lactate is as follows: l-lactic dehydrogenase (l-LDH) converts l-lactate into pyruvate by reaction with NAD+. In the presence of hexacyanoferrate(III), the resulting reduced β-nicotinamide adenine dinucleotide (NADH) is then regenerated enzymatically by diaphorase. The electrochemical detection is based on the current generated by oxidation of hexacyanoferrate(II) at an applied potential of +0.3 V vs. an Ag/AgCl reference electrode. The biosensor will be electrochemically characterized in terms of linear working range and sensitivity. Additionally, the successful practical application of the sensor is demonstrated in an extract from maize silage.
Multi-analyte biosensors may offer the opportunity to perform cost-effective and rapid analysis with reduced sample volume, as compared to electrochemical biosensing of each analyte individually. This work describes the development of an enzyme-based biosensor system for multi-parametric determination of four different organic acids. The biosensor array comprises five working electrodes for simultaneous sensing of ethanol, formate, d-lactate, and l-lactate, and an integrated counter electrode. Storage stability of the biosensor was evaluated under different conditions (stored at +4 °C in buffer solution and dry at −21 °C, +4 °C, and room temperature) over a period of 140 days. After repeated and regular application, the individual sensing electrodes exhibited the best stability when stored at −21 °C. Furthermore, measurements in silage samples (maize and sugarcane silage) were conducted with the portable biosensor system. Comparison with a conventional photometric technique demonstrated successful employment for rapid monitoring of complex media.
The immobilization of NAD+-dependent dehydrogenases, in combination with a diaphorase, enables the facile development of multiparametric sensing devices. In this work, an amperometric biosensor array for simultaneous determination of ethanol, formate, d- and l-lactate is presented. Enzyme immobilization on platinum thin-film electrodes was realized by chemical cross-linking with glutaraldehyde. The optimization of the sensor performance was investigated with regard to enzyme loading, glutaraldehyde concentration, pH, cofactor concentration and temperature. Under optimal working conditions (potassium phosphate buffer with pH 7.5, 2.5 mmol L-1 NAD+, 2.0 mmol L-1 ferricyanide, 25 °C and 0.4% glutaraldehyde) the linear working range and sensitivity of the four sensor elements was improved. Simultaneous and cross-talk free measurements of four different metabolic parameters were performed successfully. The reliable analytical performance of the biosensor array was demonstrated by application in a clarified sample of inoculum sludge. Thereby, a promising approach for on-site monitoring of fermentation processes is provided.
Optoelectronic Properties of Nanostructured Ensembles Controlled by Biomolecular Logic Systems
(2008)
A new and simple method for nanostructuring using conventional photolithography and layer expansion or pattern-size reduction technique is presented, which can further be applied for the fabrication of different nanostructures and nano-devices. The method is based on the conversion of a photolithographically patterned metal layer to a metal-oxide mask with improved pattern-size resolution using thermal oxidation. With this technique, the pattern size can be scaled down to several nanometer dimensions. The proposed method is experimentally demonstrated by preparing nanostructures with different configurations and layouts, like circles, rectangles, trapezoids, “fluidic-channel”-, “cantilever”- and meander-type structures.
Sensing charged macromolecules with nanocrystalline diamond-based field-effect capacitive sensors
(2008)
Novel concepts for flow-rate and flow-direction determination by means of pH-sensitive ISFETs
(2001)
Label-free Electrostatic Detection of DNA Amplification by PCR Using Capacitive Field-effect Devices
(2016)
A capacitive field-effect EIS (electrolyte-insulator-semiconductor) sensor modified with a positively charged weak polyelectrolyte of poly(allylamine hydrochloride) (PAH)/single-stranded probe DNA (ssDNA) bilayer has been used for a label-free electrostatic detection of pathogen-specific DNA amplification via polymerase chain reaction (PCR). The sensor is able to distinguish between positive and negative PCR solutions, to detect the existence of target DNA amplicons in PCR samples and thus, can be used as tool for a quick verification of DNA amplification and the successful PCR process.
Label-free sensing of biomolecules by their intrinsic molecular charge using field-effect devices
(2015)
A field-effect biosensor employing tobacco mosaic virus (TMV) particles as scaffolds for enzyme immobilization is presented. Nanotubular TMV scaffolds allow a dense immobilization of precisely positioned enzymes with retained activity. To demonstrate feasibility of this new strategy, a penicillin sensor has been developed by coupling a penicillinase with virus particles as a model system. The developed field-effect penicillin biosensor consists of an Al-p-Si-SiO₂-Ta₂O₅-TMV structure and has been electrochemically characterized in buffer solutions containing different concentrations of penicillin G. In addition, the morphology of the biosensor surface with virus particles was characterized by scanning electron microscopy and atomic force microscopy methods. The sensors possessed a high penicillin sensitivity of ~ 92 mV/dec in a nearly-linear range from 0.1 mM to 10 mM, and a low detection limit of about 50 µM. The long-term stability of the penicillin biosensor was periodically tested over a time period of about one year without any significant loss of sensitivity. The biosensor has also been successfully applied for penicillin detection in bovine milk samples.
Coronavirus disease 2019 (COVID-19) is a novel human infectious disease provoked by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Currently, no specific vaccines or drugs against COVID-19 are available. Therefore, early diagnosis and treatment are essential in order to slow the virus spread and to contain the disease outbreak. Hence, new diagnostic tests and devices for virus detection in clinical samples that are faster, more accurate and reliable, easier and cost-efficient than existing ones are needed. Due to the small sizes, fast response time, label-free operation without the need for expensive and time-consuming labeling steps, the possibility of real-time and multiplexed measurements, robustness and portability (point-of-care and on-site testing), biosensors based on semiconductor field-effect devices (FEDs) are one of the most attractive platforms for an electrical detection of charged biomolecules and bioparticles by their intrinsic charge. In this review, recent advances and key developments in the field of label-free detection of viruses (including plant viruses) with various types of FEDs are presented. In recent years, however, certain plant viruses have also attracted additional interest for biosensor layouts: Their repetitive protein subunits arranged at nanometric spacing can be employed for coupling functional molecules. If used as adapters on sensor chip surfaces, they allow an efficient immobilization of analyte-specific recognition and detector elements such as antibodies and enzymes at highest surface densities. The display on plant viral bionanoparticles may also lead to long-time stabilization of sensor molecules upon repeated uses and has the potential to increase sensor performance substantially, compared to conventional layouts. This has been demonstrated in different proof-of-concept biosensor devices. Therefore, richly available plant viral particles, non-pathogenic for animals or humans, might gain novel importance if applied in receptor layers of FEDs. These perspectives are explained and discussed with regard to future detection strategies for COVID-19 and related viral diseases.
Capacitive field-effect sensors modified with a multi-enzyme membrane have been applied for an electronic transduction of biochemical signals processed by enzyme-based AND-Reset and OR-Reset logic gates. The local pH change at the sensor surface induced by the enzymatic reaction was used for the activation of the Reset function for the first time.
Application of a (bio-)chemical sensor (ISFET) for the detection of physical parameters in liquids
(2003)
Functional testing and characterisation of ISFETs on wafer level by means of a micro-droplet cell
(2006)
A wafer-level functionality testing and characterisation system for ISFETs (ionsensitive field-effect transistor) is realised by means of integration of a specifically designed capillary electrochemical micro-droplet cell into a commercial wafer prober-station. The developed system allows the identification and selection of “good” ISFETs at the earliest stage and to avoid expensive bonding, encapsulation and packaging processes for nonfunctioning ISFETs and thus, to decrease costs, which are wasted for bad dies. The developed system is also feasible for wafer-level characterisation of ISFETs in terms of sensitivity, hysteresis and response time. Additionally, the system might be also utilised for wafer-level testing of further electrochemical sensors.