(Bio-)chemical Sensing and Imaging by LAPS and SPIM
- The light-addressable potentiometric sensor (LAPS) and scanning photo-induced impedance microscopy (SPIM) are two closely related methods to visualise the distributions of chemical species and impedance, respectively, at the interface between the sensing surface and the sample solution. They both have the same field-effect structure based on a semiconductor, which allows spatially resolved and label-free measurement of chemical species and impedance in the form of a photocurrent signal generated by a scanning light beam. In this article, the principles and various operation modes of LAPS and SPIM, functionalisation of the sensing surface for measuring various species, LAPS-based chemical imaging and high-resolution sensors based on silicon-on-sapphire substrates are described and discussed, focusing on their technical details and prospective applications.
| Verfasserangaben: | Tatsuo Yoshinobu, Steffi Krause, Ko-ichiro Miyamoto, Frederik WernerORCiD, Arshak PoghossianORCiD, Torsten WagnerORCiD, Michael Josef SchöningORCiD |
|---|---|
| ISBN: | 978-3-319-75219-8 |
| Signatur: | 61 VZB 26 |
| Titel des übergeordneten Werkes (Englisch): | Label-free biosensing: advanced materials, devices and applications |
| Verlag: | Springer |
| Verlagsort: | Cham |
| Dokumentart: | Teil eines Buches (Kapitel) |
| Sprache: | Englisch |
| Erscheinungsjahr: | 2018 |
| Datum der Publikation (Server): | 24.10.2018 |
| Freies Schlagwort / Tag: | Chemical imaging; Field-effect device; Light-addressable potentiometric sensor; Potentiometry |
| Erste Seite: | 103 |
| Letzte Seite: | 132 |
| Link: | https://doi.org/10.1007/5346_2017_22 |
| Zugriffsart: | campus |
| Fachbereiche und Einrichtungen: | FH Aachen / Fachbereich Medizintechnik und Technomathematik |
| FH Aachen / INB - Institut für Nano- und Biotechnologien | |
| collections: | Verlag / Springer |
