An examination of tissue engineered scaffolds in a bioreactor
- Replacement tissues, designed to fill in articular cartilage defects, should exhibit the same properties as the native material. The aim of this study is to foster the understanding of, firstly, the mechanical behavior of the material itself and, secondly, the influence of cultivation parameters on cell seeded implants as well as on cell migration into acellular implants. In this study, acellular cartilage replacement material is theoretically, numerically and experimentally investigated regarding its viscoelastic properties, where a phenomenological model for practical applications is developed. Furthermore, remodeling and cell migration are investigated.
| Author: | Angela Niedermeyer, Bei Zhou, Gözde Dursun, Aysegül Temiz ArtmannORCiD, Bernd Markert |
|---|---|
| DOI: | https://doi.org/10.1002/pamm.201610038 |
| ISSN: | 1617-7061 |
| Parent Title (English): | Proceedings in Applied Mathematics and Mechanics PAMM |
| Publisher: | Wiley-VCH |
| Place of publication: | Weinheim |
| Document Type: | Article |
| Language: | English |
| Year of Completion: | 2016 |
| Volume: | 16 |
| Issue: | 1 |
| First Page: | 99 |
| Last Page: | 100 |
| Note: | Joint Annual Meeting of DMV and GAMM 2016, 87th Annual Meeting of the International Association of Applied Mathematics and Mechanics (GAMM) and Deutsche Mathematiker-Vereinigung (DMV), Braunschweig, DE, Mar 7-11, 2016 |
| Link: | https://doi.org/10.1002/pamm.201610038 |
| Zugriffsart: | weltweit |
| Institutes: | FH Aachen / Fachbereich Chemie und Biotechnologie |
| FH Aachen / IfB - Institut für Bioengineering | |
| collections: | Verlag / Wiley-VCH |
