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LAPS are field-effect-based potentiometric sensors which are able to monitor analyte concentrations in a spatially resolved manner. Hence, a LAPS sensor system is a powerful device to record chemical imaging of the concentration of chemical species in an aqueous solution, chemical reactions, or the growth of cell colonies on the sensor surface, to record chemical images. In this work, multi-chamber 3D-printed structures made out of polymer (PP-ABS) were combined with LAPS chips to analyse differentially and simultaneously the metabolic activity of Escherichia coli K12 and Chinese hamster ovary (CHO) cells, and the responds of those cells to the addition of glucose solution.
Changes in intestinal microflora in rats induced by oral exposure to low lead (II) concentrations
(2015)
Influence of refrigerated storage on tensile mechanical properties of porcine liver and spleen
(2015)
Verbrennungsmotoren
(2015)
The cooling process in induction based crucible melting furnaces for Industrial applications is one of the important and challenging factors in production and safety engineering. Accordingly, proper implementation of the cooling system of the furnace using optimum cooling guides and fail-safe features are critical in order to improve the safety of the process. Regarding this, manufacturing of porous material with high electrical isolation for the drainage segments of the cooling channels is examined in this study. Consequently, various geometries with different porosities using glass and ceramic powder are fabricated using Selective Laser Sintering (SLS) process. The manufactured parts are examined in a prototype furnace testing and the feasibility of the SLS manufacturing of parts for this application is discussed.
Geotechnik
(2015)
In der nationalen und der europäischen Normung werden die geotechnischen Aufgaben zwecks Mindestanforderungen an Baugrunduntersuchung, rechnerische Nachweise und Überwachung der Ausführung in drei Klassen (Kategorien) eingeteilt. Sie richten sich nach der zu erwartenden Reaktion des Baugrundes, nach dem geotechnischen Schwierigkeitsgrad des Tragwerks und seiner Einflüsse auf die Umgebung.
In DIN 4020 wurde die Einteilung bezüglich Art und Umfang der geotechnischen Untersuchungen bereits verbindlich eingeführt.
Geotechnik
(2015)
Konstruktion und Raumform im Kirchenbau der Moderne : Die Längsbinderkirchen von Hans Herkommer
(2015)
System mit Hülle - Die innovativen Bauten der Steiff-Spielwarenfabrik in Giengen an der Brenz
(2015)
We present an electromechanically coupled Finite Element model for cardiac tissue. It bases on the mechanical model for cardiac tissue of Hunter et al. that we couple to the McAllister-Noble-Tsien electrophysiological model of purkinje fibre cells. The corresponding system of ordinary differential equations is implemented on the level of the constitutive equations in a geometrically and physically nonlinear version of the so-called edge-based smoothed FEM for plates. Mechanical material parameters are determined from our own pressure-deflection experimental setup. The main purpose of the model is to further examine the experimental results not only on mechanical but also on electrophysiological level down to ion channel gates. Moreover, we present first drug treatment simulations and validate the model with respect to the experiments.
Development and Testing of a Low NOx Micromix Combustion Chamber for an Industrial Gas Turbine
(2015)
We present a robotic tool that autonomously follows a conversation to enable remote presence in video conferencing. When humans participate in a meeting with the help of video conferencing tools, it is crucial that they are able to follow the conversation both with acoustic and visual input. To this end, we design and implement a video conferencing tool robot that uses binaural sound source localization as its main source to autonomously orient towards the currently talking speaker. To increase robustness of the acoustic cue against noise we supplement the sound localization with a source detection stage. Also, we include a simple onset detector to retain fast response times. Since we only use two microphones, we are confronted with ambiguities on whether a source is in front or behind the device. We resolve these ambiguities with the help of face detection and additional moves. We tailor the system to our target scenarios in experiments with a four minute scripted conversation. In these experiments we evaluate the influence of different system settings on the responsiveness and accuracy of the device.
Offene und geschlossene WLAN: Rechtliche Hürden bei Betrieb eines öffentlichen Internetzugangs
(2015)
Small Spacecraft in Planetary Defence Related Applications–Capabilities, Constraints, Challenges
(2015)
In this paper we present an overview of the characteristics and peculiarities of small spacecraft missions related to planetary defence applications. We provide a brief overview of small spacecraft missions to small solar system bodies. On this background we present recent missions and selected projects and related studies at the German Aerospace Center, DLR, that contribute to planetary defence related activities. These range from Earth orbit technology demonstrators to active science missions in interplanetary space. We provide a summary of experience from recently flown missions with DLR participation as well as a number of studies. These include PHILAE, the lander recently arrived on comet 67P/Churyumov-Gerasimenko aboard ESA’s ROSETTA comet rendezvous mission, and the Mobile Asteroid Surface Scout, MASCOT, now underway to near-Earth asteroid (162173) 1999 JU3 aboard the Japanese sample-return probe HAYABUSA-2. We introduce the differences between the conventional methods employed in the design, integration and testing of large spacecraft and the new approaches developed by small spacecraft projects. We expect that the practical experience that can be gained from projects on extremely
compressed timelines or with high-intensity operation phases on a newly explored small solar system body can contribute significantly to the study, preparation and realization of future planetary defence related missions. One is AIDA (Asteroid Impact & Deflection Assessment), a joint effort of ESA,JHU/APL, NASA, OCA and DLR, combining JHU/APL’s DART (Double Asteroid Redirection Test) and ESA’s AIM (Asteroid Impact Monitor) spacecraft in a mission towards
near-Eath binary asteroid (65803) Didymos.
Cytochrome b5 Is a Major Determinant of Human Cytochrome P450 CYP2D6 and CYP3A4 Activity In Vivo s
(2015)
7. Studie Vertriebskompass 2015/2016 / durchgeführt von der FH Aachen und der Siers & Collegen GmbH
(2015)
Opioid Analgesia in P450 Gene Cluster Knockout Mice: A Search for Analgesia-Relevant Isoforms
(2015)
High-k perovskite oxide of barium strontium titanate (BST) represents a very attractive multi-functional transducer material for the development of (bio-)chemical sensors. In this work, a Si-based sensor chip containing Pt interdigitated electrodes covered with a thin BST layer (485 nm) has been developed for multi-parameter chemical sensing. The chip has been applied for the contactless measurement of the electrolyte conductivity, the detection of adsorbed charged macromolecules (positively charged polyelectrolytes of polyethylenimine) and the concentration of hydrogen peroxide (H2O2) vapor. The experimental results of functional testing of individual sensors are presented. The mechanism of the BST sensitivity to charged polyelectrolytes and H2O2 vapor has been proposed and discussed.
System und Verfahren zur Durchführung von chemischen, biologischen oder physikalischen Reaktionen
(2015)
Inkompressible Strömungen
(2015)
Simulating the electromagnetic‐thermal treatment of thin aluminium layers for adhesion improvement
(2015)
A composite layer material used in packaging industry is made from joining layers of different materials using an adhesive. An important processing step in the production of aluminium-containing composites is the surface treatment and consequent coating of adhesive material on the aluminium surface. To increase adhesion strength between aluminium layer and the adhesive material, the foil is heat treated. For efficient heating, induction heating was considered as state-of-the-art treatment process. Due to the complexity of the heating process and the unpredictable nature of the heating source, the control of the process is not yet optimised. In this work, a finite element analysis of the process was established and various process parameters were studied. The process was simplified and modelled in 3D. The numerical model contains an air domain, an aluminium layer and a copper coil fitted with a magnetic field concentrating material. The effect of changing the speed of the aluminium foil (or rolling speed) was studied with the change of the coil current. Statistical analysis was used for generating a general control equation of coil current with changing rolling speed.
Zero energy solutions for multifunctional steel intensive commercial buildings (ZEMUSIC) - EUR 27627
(2015)
The broad commercial objective of this project was the sustainable value creation in steel building technology by addressing the ways in which significant energy reductions can be made in the operation phase of multi-storey commercial buildings. A review on energy efficient commercial buildings in Europe has been carried out consisting of several case studies from different countries. The project included development of zero-energy concepts for reducing energy demand as well as concepts for heating, cooling and ventilation systems by utilising renewable energy sources in three different climates. Also alternative structural frame solutions were developed and analyzed in respect of structural and MEP (mechanical, electrical and plumbing solutions) features. An innovative long span floor system with integrated MEP routings promises a cost effective alternative for sophisticated ventilation distribution and radiant heating and cooling systems, allowing for high energy efficiency and high quality interior climate. The report includes also review of best architectural practices for integrated renewable energy solutions including different design strategies for building facades of zero energy buildings. Interesting results and design basis are also presented for steel energy pile concept, where structural foundation piles are utilized for ground energy harvesting. Life cycle cost calculations for near zero energy office building based on developed technologies show that a near zero energy construction is also profitable. The results and work methods of the project have been summarized in the form of design guidance that offers designers the knowledge gained in a form that can be easily understood.
We introduce a new way to measure the forecast effort that analysts devote to their earnings forecasts by measuring the analyst's general effort for all covered firms. While the commonly applied effort measure is based on analyst behaviour for one firm, our measure considers analyst behaviour for all covered firms. Our general effort measure captures additional information about analyst effort and thus can identify accurate forecasts. We emphasise the importance of investigating analyst behaviour in a larger context and argue that analysts who generally devote substantial forecast effort are also likely to devote substantial effort to a specific firm, even if this effort might not be captured by a firm-specific measure. Empirical results reveal that analysts who devote higher general forecast effort issue more accurate forecasts. Additional investigations show that analysts' career prospects improve with higher general forecast effort. Our measure improves on existing methods as it has higher explanatory power regarding differences in forecast accuracy than the commonly applied effort measure. Additionally, it can address research questions that cannot be examined with a firm-specific measure. It provides a simple but comprehensive way to identify accurate analysts.